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In conversation with Dr Robert B Nussenblatt
Dr Robert B Nussenblatt is Chief of the Laboratory of Immunology at the National Eye Institute, an eminent ocular immunologist and an expert in clinical research design and conduct. Describe the success or relevance of the SUN project. The Standardization...
Advanced vestibular Schwannoma case report
Vestibular Schwannoma is a benign, slow growing tumour which usually presents with unilateral hearing loss. It causes symptoms and findings on ophthalmic examination when the diagnosis is delayed. Ophthalmic findings may be related to the effect of the expanding mass...
MicroRNAs in cataract
In an ageing population cataract formation is one of the leading causes of blindness. Cataracts are caused by a failure to clear accumulating aggregated proteins in the lens. MicroRNAs are small non-coding transcripts which bind to specific mRNAs acting at...
Which factors predispose to pingecula development in a rural Chinese population?
The authors report a cross-sectional study which aimed to determine the prevalence and risk factors for developing pingecula in a rural Chinese population near Shanghai. Nine hundred and fifty-nine persons were recruited from a single village and asked to complete...
ILM peeling in primary rhegmatogenous retinal detachment
This author retrospectively analysed the correlation between internal limiting membrane (ILM) peeling and the occurrence of a postoperative epiretinal membrane (ERM) in patients who underwent vitrectomy for rhegmatogenous retinal detachment (RD). There were 135 medical records investigated. Seventy patients underwent...
LASEK vs. epi-LASIK for myopia: meta-analysis
Previous studies have produced inconsistent conclusions on the relative benefits between LASEK vs. Epi-LASIK. LASEK uses 20% alcohol to separate an epithelial flap from the Bowman membrane. After ablation, the epithelial flap is repositioned onto the cornea. Epi-LASIK creates the...
Assessing the quality of scars from incisions made by a Colorado needle or a scalpel
Traditional teaching has held the best scars are achieved with cold steel although no previous study has formally investigated this hypothesis in oculoplastic surgery. This paper describes a non-randomised cross-sectional study comparing the scar quality achieved from cold steel with...
The effect of everolimus on retinal pigment epithelium and proliferative vitreo-retinopathy
The principal cells involved in proliferative vitreo-retinopathy (PVR) are retinal pigment epithelial cells (RPE). Everolimus is a drug used in renal cell carcinoma which targets and inhibits a key regulatory protein in cancer (mTOR). In this study, the authors investigated...
Local surgical treatment of trigeminal neuralgia
This is a retrospective review of a new surgical treatment of intractable periorbital neuropathic pain. Five patients with post-herpetic (three), post-traumatic (one) and idiopathic (one) neuralgia underwent transection of the nerves supplying the dermatomes affected by the neuropathic pain. The...
Features, treatment and prevention of conjunctival inclusion cysts
Conjunctival inclusion cyst is a rare complication of strabismus surgery and generally develops at the point of muscle reattachment, caused by implantation of conjunctival epithelium. The authors aimed to determine the rate of its development after strabismus surgery and consider...
