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Patterns of binocular diplopia in giant cell arteritis (GCA)

Giant cell arteritis (GCA) is a granulomatous vasculitis that targets medium and large sized vessels. Binocular diplopia has been reported in a small number of patients with visual manifestations of GCA. It can be caused by ischaemia in any segment...

SS-OCT assessment of ITC after phacoemulsification

This is a multicentre randomised controlled trial of 22 patients with primary angle closure glaucoma with peripheral anterior synechia and peripheral primary angle closure glaucoma (PACG) with peripheral anterior synechia (PAS) detected by indentation gonioscopy was randomised into two groups....

Predictive value of OCT biomarkers on visual outcome in retinal vein occlusion

This was a retrospective study. The cohort included 163 eyes from patients diagnosed with retinal vein occlusion (RVO) aged 18 years or older. The primary endpoints were the mean change in best corrected visual acuity (BCVA) at baseline to follow-up...

Part 2: Her Royal Highness The Duchess of Edinburgh Visits Ethiopia with Orbis

Her Royal Highness The Duchess of Edinburgh has today taken part in a historic trachoma elimination conference in Addis Ababa, Ethiopia.

Incidence and risk factors of late in the bag intraocular lens dislocation

The aim of this study was to identify risk factors for late in the bag dislocation over a 21 year period. Worldwide the incidence varies from 0.05% to 3.0%. In this Swedish study they report an increase in incidence in...

Myopia-related strabismus – heavy eye syndrome

Introduction Myopia can be associated with any type of strabismus, but high myopia has increased frequency of esotropia and vertical heterotropia. The incidence and severity of the strabismus increases with the degree of myopia and age of the patient. Classification...

The PMFA Journal - April/May 2019 issue available

FEATURES IN THIS ISSUE: An update on BIA-ALCL by Shadi Ghali / The importance of teamwork and leadership in the management of patients in burns centres by Emily Claire Taylor, Steven LA Jeffery / Focus: Opinions on regulation by Dalvi Humzah, Paul Charlson, Andrew Rankin / CPD certified: Hand rejuvenation with injectable fillers by Medhat Abdelmalek AND MUCH MORE...

Nicotine accelerates diabetes induced retinal changes

This study investigated the influence of nicotine in an experimentally induced diabetic rat model. They used non-invasive high-resolution spectral domain optical coherence tomography (SD-OCT) imaging to provide quantitative information on the temporal alterations of retinal structures at the micrometer resolution...

ANGPTL-4 inhibition reduces inflammation in diabetic retinopathy

Diabetic retinopathy (DR) is the most common cause of blindness in working-age humans, and numbers are rising due to increased cases of type 2 diabetes (T2D). T2D is associated with increased obesity and dyslipidaemia, which is a major risk factor...

Complement Factor H and Factor H-Like protein are expressed in human RPE cells

The role of inflammation in age-related macular degeneration (AMD) is well documented and the association of AMD with the inflammatory marker C-reactive protein (CRP) and members of the complement system underline the role of complements in AMD. Human complement factor...

A pulsatile pump in the TM, a new concept in trabecular outflow research

This is a research article where the authors propose a new model in conceptualising the mechanisms involved in the aqueous outflow at the trabecular meshwork (TM). The authors demonstrated evidence of a pump within the Schlemm’s canal. A pulse generated...

Understanding the extracellular matrix in uveal melanoma

This review examines how the extracellular matrix (ECM) is remodelled throughout uveal melanoma development, from the eye to the liver. Uveal melanoma, the most common primary intraocular malignancy in adults, carries a poor prognosis due to its propensity for hepatic...