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Risk factors for non-arteritic ischaemic optic neuropathy in an Asian population
The authors reviewed the medical records of 45 Korean patients with non-arteritic anterior ischaemic optic neuropathy (NAION) and 45 healthy controls, in order to determine risk factors for the condition in an Asian population. Previous studies looking at risk factors...
Who will benefit from cataract surgery?
The need for cataract surgery is expected to rise dramatically in the future due to the increasing proportion of elderly citizens and increasing demands for optimum visual function. The aim of this study was to provide an evidence-based recommendation for...
Intravitreal aflibercept for diabetic macular oedema
The VISTA and VIVID randomised phase 3 trial were designed to compare the efficacy and safety of intravitreal aflibercept injections versus laser photocoagulation for diabetic macular oedema (DMO). A total of 872 patients with centrally involving DMO were recruited, and...
Is an increased homocysteine level associated with greater risk of AMD?
Basic research studies have implicated homocysteine in causing vascular endothelial dysfunction and inflammation, and this has been borne out in large observational studies which suggested that elevated homocysteine is associated with increased risk of cardiovascular disease. In order to determine...
Iranian prevalence of strabismus and heterophoria
Previous studies in parts of Iran report a childhood prevalence of strabismus of 1.2 to 2.3%. The authors aimed to evaluate the prevalence of strabismus in underserved rural areas of Iran in all age groups. In 2015 they conducted a...
VEGF and axial length (RVU)
The authors of this paper set out to examine whether the concentrations of VEGF in the vitreous were associated with refractive error and axial length in eyes without retinal disease, except of macular holes or epiretinal membranes. A vitreous sample...
Effect of phacoemulsification on trabeculectomy function
Previous studies have reported cataract surgery post trabeculectomy to be detrimental to IOP control. Conversely, other studies have reported phacoemulsification performed before trabeculectomy as a factor for bleb failure. The objective of this retrospective case control study was to evaluate...
Cataract in patients with pseudoexfoliation syndrome
The authors present a prospective comparative study in 43 patients with (group 1) or without (group 2) pseudoexfoliation (PXF) undergoing cataract surgery. Anterior capsule samples were obtained in all patients and analysed for signs of apoptosis by using special staining...
Lucentis for pseudophakic CMO
Pseudophakic cystoid macular oedema (CMO) develops angiographically in up to 20-30% after uneventful phacoemulsification. This study aimed to evaluate the potential efficacy and safety of intravitreal ranibizumab in patients with pseudophakic CMO after cataract surgery. Seven eyes were included in...
Retinal vessel diameter in pseudoexfoliation
Pseudoexfolation (PEX) is characterised by deposition of fibrillary extracellular material on ocular and extraocular tissue. Studies have shown that deposition in vascular structures cause hypoxia and ischaemia. In the eye, a decrease in blood supply to the optic nerve can...
Benefit of selenium and vitamin D supplementation in thyroid eye disease
There is some limited evidence of as association between thyroid eye disease (TED) and nutritional deficiencies including selenium and vitamin D. Prior studies show that selenium can reduce TPO-antibody concentrations and improve hypothyroidism and post-partum thyroiditis. Limited evidence also shows...
