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Crystalline keratopathy in monoclonal gammopathy of undetermined significance
Monoclonal gammopathies encompass a group of plasma cell disorders characterised by the excessive production of abnormal monoclonal immunoglobulins in the bloodstream [1]. This category includes multiple myeloma, monoclonal gammopathy of undetermined significance (MGUS), amyloidosis and other lymphoproliferative disorders. Monoclonal gammopathy...Getting started in ophthalmology: Advice for new doctors
Starting your first rotation in ophthalmology is exciting and a little daunting. As the start date approaches, the nerves may start to creep in. What’s expected of me? How much ophthalmology am I supposed to know? How will the on-calls...Optical bodies band together in name of sustainability
A group of key optical bodies representing practitioners, practice owners and suppliers has come together to release a statement of intent with aims for the professions and industry in terms of long term environmental sustainability. Harjit Sandhu, Managing Director at...
Carbonic anhydrase II autoantibody specificity in retinopathy
Autoimmune retinopathy (AR) can be divided into three different categories, paraneoplastic retinopathy, including recoverin-associated retinopathy and melanoma-associated retinopathy, non-paraneoplastic autoimmune retinopathy, combined paraneoplastic optic neuropathy and retinopathy (CAR). These conditions are characterised by circulating anti-retinal autoantibodies, possibly due to a...
Persistence of Ebola virus in ocular fluid during convalescence
The most recent Ebola outbreak has infected over 26,300 patients, but also resulted in the highest number of survivors in history. Uveitis has been described during the convalescent period, but Varkey and colleagues report, for the first time, finding viable...
Comparison of ganglion cell thinning in glaucoma vs. macular hole repair
This prospective study compared the changes in the photopic negative response of the focal macular electroretinogram (fmERG) caused by retinal ganglion cell complex (GCC) thinning at the macula between patients with open angle glaucoma (OAG) and 12 months after successful...
Differences of the anterior segment parameters in children with Down syndrome
This cross-sectional study was designed in order to demonstrate the differences in anterior segment parameters in children with trisomy 21. This is important as it may impact on surgical planning when undertaking procedures in the anterior segment such as corneal...
Does Ozurdex affect perfusion status in vein occlusion?
Ozurdex (intravitreal dexamethasone implant) has been approved by National Institute of Health & Care Excellence (NICE) for treatment of patients with macular oedema associated with vein occlusion. This study looks at the change in peripheral perfusion status in patients with...
OCT angiography sign after whiplash
Berlin’s oedema is a rare condition following blunt ocular injury and a rare finding after whiplash injury. This case describes a 48-year-old male who suffered a seventh vertebrae fracture from a traffic accident. Two days later, decreased left eye visual...
Cutaneous malignant melanoma metastasis to pseudophakic lens
Metastases to the eye and orbit are rare and intraocular cutaneous malignant melanoma metastasis (ICMM) is exceedingly rare, representing around 5%. There have only been three previous cases of ICMM to the lens in the literature, all of which presented...
Could internuclear ophthalmoplegia aid differential diagnosis in demyelinating conditions?
The authors present a retrospective review of individuals diagnosed with either neuromyelitis optica spectrum disorder (NMOSD) or multiple sclerosis (MS). The aim of the study was to assess the prevalence of internuclear ophthalmoplegia (INO) in both groups over a 10-year...
