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γδ T cell depletion does not affect fungal keratitis

1 August 2015 | | EYE - Cornea, EYE - General | CFW, Cytokines, FK, Fungal keratitis, IL-17, Neutrophils, calcofluor WHITE, fungal keratitis, γδ T cells
Fungal keratitis (FK) is a blinding condition prevalent in agricultural areas of countries such as India and China. The fungus enters the cornea and induces an inflammatory response which leads to tissue damage. Neutrophils are the earliest infiltrating immune cells...

Cyclosporine A and pterygium fibroblasts

1 October 2015 | | EYE - Cornea, EYE - General
The matrix metalloproteinases (MMP) are a family of structurally related zinc-dependent extracellular matrix degrading proteinases that have been implicated in facilitating the migration and growth of pterygia. Both MMP- 3 and MMP-13 were found to be overexpressed in the fibroblasts...

Effective management of dry eye and ocular surface disease

4 August 2021 | | EYE - General
Experts recommend a consistent approach to diagnosis, therapeutic targeting by disease subtype and escalation of therapy when tear substitutes are not sufficient. Experts call for a consistent, unified approach to diagnosis of dry eye disease (DED), with a new simple...

A case of progressive supranuclear palsy-like syndrome following aortic aneurysm repair

1 August 2015 | | EYE - Neuro-ophthalmology
This original article illustrates the case of an 18-year-old woman who developed progressive supranuclear palsy-like syndrome following an uneventful aortic aneurysm repair. The patient was unaffected for the first 48 hours after surgery and then developed dysarthria, dysphagia (requiring a...

Stem cell therapy for Parkinson’s disease: researching for an 
effective cure

1 December 2015 | | EYE - Neuro-ophthalmology
Neurodegenerative diseases are characterised by the chronic and progressive loss of neurons, which in turn results in loss of cognitive and physical functions. The World Health Organization has estimated that the disability-adjusted life years lost from neurological disease was about...

Lord Trees and Baroness Sugg call to end Neglected Tropical Diseases with charity coalition at Westminster event

9 June 2022
UK Coalition against Neglected Tropical Diseases works alongside co-host parliamentary reception in the House of Lords.

A social media triumph for Ukraine

27 March 2023 | Written by | Ukraine, OAEE, charity
Following the outbreak of the war in Ukraine in February last year, the charity Ophthalmic Aid to Eastern Europe (OAEE) set about trying to gather ophthalmic equipment and supplies for Ukraine.

Supranuclear ocular motility disorders

1 June 2022 | | EYE - Neuro-ophthalmology, EYE - General
Figure 1: Bilateral INO Introduction Complex ocular motility disorders are a diagnostic challenge. These patients come with very complex ocular motility presentations and require a careful and detailed assessment in order to find the correct diagnosis and arrange appropriate investigations....

Amnion-assisted conjunctival epithelial redirection (ACER): Enhancing stem cell transplantation treatment of total limbal stem cell deficiency

1 April 2019 | | EYE - Cornea, EYE - General
An exploration of Professor Harminder Dua’s recent work using a technique called amnion-assisted conjunctival epithelial redirection (ACER) to aid the success of conjunctival-limbal grafting procedures. ACER provides a refined way to use amniotic membrane (amnion), such as Omnigen® (NuVision® Biotherapies,...

Deciphering dark retinal patches

3 October 2024 | | EYE - Vitreo-Retinal
We present a case of bilateral extensive dark without pressure (DWP) located outside the retinal vascular arcades in a young female. This retinal finding is benign but, in some instances, darkened retinal patches could be associated with potential sight-threatening conditions....

NHS Lothian donates ophthalmic equipment to Ukraine

24 July 2023 | NHS, NHS Lothian, Aid, Ophthalmology, Charity, International, Peter Cackett, Edinburgh, Ukraine, Kyiv
Following the outbreak of the war in Ukraine, an NHS Lothian doctor has set his sights on distributing donations to his Eastern European counterparts.

Sunflower Scotland delivers aid to Ukraine

8 July 2024 | ukraine, donations, charity, humanitarian, international
Sunflower Scotland has been helping Ukraine since the second week of the war, first as volunteers and later as a registered charity.