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3064 results found

Pupil responses in diabetes

This study aimed to investigate pupillary involvement in patients with type 2 diabetes mellitus (DM) and to evaluate any relationship between severity of diabetic retinopathy (DR) and pupillary responses. Participants included 133 individuals in four groups: proliferative DR (n=21), non-proliferative...

Do patients with prolactinomas using dopamine agonist drugs have autonomic dysfunction?

This prospective study aimed to determine whether there is autonomic dysfunction in patients with prolactinomas using dopamine agonist (DA) drugs by measuring static and dynamic pupillary responses using an automatic pupillometric device.Included were 25 eyes from 25 patients who were...

RCT of surgery to correct asymmetrical DVD

This study compared the efficacy of two procedures: (1) bilateral symmetrical anteriorisation of the inferior oblique (AIO) and (2) combined resection and AIO, in cases of asymmetrical dissociated vertical deviation (DVD). This was a prospective randomised controlled trial including 54...

Test combination which could detect prodromal Alzheimer disease

The authors prospectively recruited a convenience sample of individuals aged over 65 and either with a diagnosis of mild cognitive impairment (MCI) due to Alzheimer disease or normal cognition. Other types of dementia and severe neurological conditions were excluded. All...

OCT in neuro-ophthalmology: A practical overview

From multiple sclerosis to raised intracranial pressure, optical coherence tomography is transforming how we diagnose, monitor and predict outcomes across the full spectrum of neuro-ophthalmic disease. Optical coherence tomography (OCT) is a rapid imaging method that utilises light waves to...

Quality matters in the management of serious eye disorders

The author discusses the first quality standard for serious eye disorders from NICE and takes a look at new care models for enhanced service delivery. Patient backlogs pose risks to patient safety, with research showing that people are losing sight...

Review of international telemedicine infrastructure for ROP

This review aimed to review the information and communications technology available for telemedicine, the internet access and economic status of countries at greater risk for higher prevalence of ROP, the framework of established ROP telemedicine programmes, and the cost-effectiveness of...

Moorfields: The 2025 macula course

The 2025 Macula course will take place from 2nd - 5th June 2025. Bookings are now open. Retinal diseases are a major cause of blindness. Diagnostic investigations, understanding of disease mechanisms, new therapies, and the evidence base, have all evolved...

Atopic dermatitis: Risk of glaucoma progression?

This population-based retrospective cohort study from December 5, 2003 to December 3, 2018 examined 528,469 patients with glaucoma with a diagnosis of atopic dermatitis (AD) based on diagnostic claim codes from the TriNetX Research Network, which contains real-time information on...

Visual prognosis in Irish Leber’s hereditary optic neuropathy

Leber’s hereditary optic neuropathy (LHON) is an inherited optic neuropathy This paper presents a retrospective review of clinical data from patients with LHON presenting to an Irish tertiary referral ophthalmic hospital. Clinical and genetic characteristics were assessed for useful biomarkers...

OVD influences

This prospective case series provides data on a previously uninvestigated area. Eyes due to have routine phakoemulsification were divided into six groups according to ophthalmic viscosurgical device (OVD) type. After cataract extraction aphasic refraction using intraoperative aberrometry with the ocular...

ROCK inhibition after descemetorhexis without endothelial keratoplasty: a small but timely Indian RCT

The authors present a single-centre, prospective, randomised, comparative clinical trial (RCT) of 24 eyes of 24 patients with mild-to-moderate Fuchs endothelial corneal dystrophy (FECD) undergoing combined phacoemulsification and a standardised 4mm central descemetorhexis without endothelial keratoplasty (DWEK), with or without...