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Injection of methotrexate into silicone oil-filled eyes for grade C PVR

Methotrexate (MTX) is an antineoplastic antimetabolite with immunosuppressant properties. Folate antagonism is known to contribute to the antiproliferative effects of MTX, and release of adenosine from cells and inhibition of polyamines may explain its anti-inflammatory effects. These activities contribute to...

Patient education in ophthalmology: Contact lens wearers

Contact lenses provide effective vision correction for approximately 4.5 million people in the UK [1]. However, their improper use and poor hygiene practices contribute to increased risk of contact lens-related complications. Furthermore, a study in the USA showed that 99%...

In conversation with Christopher Liu OBE

Eye News caught up with Christopher Liu following his recent appointment by Her Majesty Queen Elizabeth II as an Officer of the Most Excellent Order of the British Empire for Services to Ophthalmology. Christopher Liu OBE. Congratulations on your recent...

All eyes on Twiggy as she fronts new campaign warning us: don’t lose focus of your eye health

Dame Twiggy Lawson fronts a new public awareness campaign focused on eye health, as cases of macular disease increase with our ageing population.

Practice tips: Directions in cataract surgery services and preventing postcataract endophthalmitis

Future directions in the delivery of high quality cataract surgery services and approved intracameral prophylactic approaches to lowering the risk of postcataract infective endophthalmitis were debated by consultant ophthalmic surgeons in a recent London seminar, held at the Royal Society...

Corporate M&A pace gathers momentum

Intensifying franchise competition, maturing product development pipelines and looming loss of exclusivity spur renewed merger and acquisition (M&A) activity in the ophthalmics sector. Rod McNeil reviews recent deals and related strategic developments. AbbVie to acquire Allergan in $63 billion mega-combination,...

Effective management of dry eye and ocular surface disease

Experts recommend a consistent approach to diagnosis, therapeutic targeting by disease subtype and escalation of therapy when tear substitutes are not sufficient. Experts call for a consistent, unified approach to diagnosis of dry eye disease (DED), with a new simple...

Maximising the ocular surface prior to cataract surgery: The old and the new modalities of treatment

Cataract surgery is among the most commonly performed surgical procedures worldwide. Over time, it has evolved from a lens-extraction procedure into a refractive intervention that demands meticulous perioperative planning and precision to achieve optimal outcomes. Optimisation of the ocular surface...

Quantifying ductions and fields of BSV

The authors aimed to evaluate current clinical practice of quantifying ductions and fields of binocular single vision (BSV) in the UK and Ireland. An online questionnaire was used and was circulated via the British & Irish Orthoptic Society (BIOS) member...

Progressive myelination of the retinal nerve fibre layer: Acquired or incidental?

*Co-first authors.Myelinated retinal nerve fibres are retinal nerve fibres encased by a myelin sheath, located anterior to the lamina cribrosa [1]. First described by Virchow in 1856, a myelinated retinal nerve fibre layer (RNFL) appears as a whitish, feathery patch...

My Top Five: Innovations in the diagnosis of ocular tumours

Ocular tumours can vary widely in origin, from benign growths to metastases from distant disseminated malignancies. Although rare, ocular tumours pose a significant health and economic burden globally, with ocular cancers accounting for 0.2% of all diagnosed malignancies in the...

Optegra celebrates 15th anniversary and announces expansion plans

Specialist eye hospital Optegra marks its 15th anniversary this month, having opened its first UK hospital in Guildford in 2008.