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Using OCT to screen and monitor Alzheimer’s disease
Alzheimer’s disease (AD) is a neurodegenerative illness characterised by progressive decline in cognitive function. AD is the main cause of dementia worldwide. Over recent years researchers have strived to find biomarkers to diagnose AD, particularly in the early stages of...
Comparison of methods of central corneal thickness measurement in glaucoma
This prospective study was done to compare the accuracy and reproducibility of central corneal thickness measured by hand-held and disc-mounted ultrasound pachymeter in glaucoma patients. Sixty-five patients were included in the study. Patients with corneal diseases, corneal astigmatism >3 diopters...
Measurement considerations in OCT results with suspected glaucoma
The purpose of this study was to determine retinal nerve fibre (RNFL) thickness parameters and assess the relationship between the cup-to-disc (CD) ratio and RNFL measurements of paediatric patients who had optic nerve appearance suspicious for glaucoma based on enlarged...
Retinal changes prior to hydroxychloroquine toxicity
In this retrospective longitudinal study, the authors examined changes in retinal layer thickness in patients taking hydroxychloroquine without evidence of retinopathy. Patients were drawn from a hydroxychloroquine screening clinic and required at least two OCT scans, at least one year...
Changes in the choroid after atropine for amblyopic and fellow eyes
The purpose of this study was to compare the effects of atropine on the thickness and structure of the choroid between amblyopic and fellow eyes. This study included 16 patients: five males, 11 females. Median age at ocular coherence tomography...
Light tolerance in infectious keratitis
The authors presented the findings of a study that aimed to identify the maximum irradiance (power received by a surface per unit area) that can be tolerated by photophobic patients with infectious keratitis (IK). They recruited 30 patients (14 women...
Choroidal and RNFL thickness in patients with OSAS
In obstructive sleep apnoea syndrome (OSAS), hypoxia secondary to repetitive apnoeic episodes leads to blood pressure variations and haemodynamic changes. There is also intermittent activation of the sympathetic system when the patient is aroused from sleep during apnoeic episodes. OSAS...
OCT choroidal signs for congenital retinal pigment epithelium hypertrophy
Congenital hypertrophy of the retinal pigment epithelium (CHRPE) on ocular coherence tomography (OCT) has the characteristic sign of RPE thickening and hyper reflectivity. However, the underlying choroid characteristics remain under researched. This retrospective study utilised data from an ophthalmic oncology...The founder of modern ophthalmology: Sir William Stewart Duke-Elder
A recent article in Eye News by Blaikie & King highlighted the extraordinary contribution made to the profession of ophthalmology by Sir William Stewart Duke-Elder. The author felt it appropriate to take a further in-depth look at the remarkable career...
GA vs. office measures of axial length
Axial lengths were compared in an office setting versus under general anaesthetic (GA) to determine if awake office measures are feasible and whether differences in measures occur in both settings. The study included 33 eyes of 19 children; 84% male,...
