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Ectopia lentis management

This review discusses the management of non-traumatic ectopia lentis in the paediatric population focussing on the variety of surgical options for these patients. The review considers visual sequelae and conservative management, limitations for surgery with respect to historical and current...

Visual outcomes after surgery for primary RRD in era of microincision vitrectomy

This is a prospective, multicentre, nationwide study between 2016 and 2017, to investigate the preoperative ocular factors, surgical techniques (pars plana vitrectomy (PPV) or scleral buckling (SB), or combined procedures) for rhegmatogenous retinal detachment (RRD) and postoperative best corrected visual...

Effective treatment for rare sight-threatening infection

A drug candidate, based on pioneering UCL and Moorfields Eye Hospital research and currently under development by SIFI S.p.A., has been found to be highly effective in treating a rare sight-threatening eye infection in a new international clinical trial.

Real-world experience and outcomes of SLT laser used as a first-line treatment in ocular hypertension patients in a United Kingdom National Health Service setting

The management of raised intraocular pressure (IOP) in the context of ocular hypertension (OHT) and primary open angle glaucoma (POAG) remains a major contributor to the workload of ophthalmology units across the UK. Treatment of these conditions has historically centred...

The results of the last survey Feb22

This edition’s survey took a slightly different tack and tried to look at the problems we face in litigation. Litigation is unpleasant. It is horrible being involved in it and the process of litigation can be extremely stressful. From the...

The PMFA Journal - April/May 2019 issue available

FEATURES IN THIS ISSUE: An update on BIA-ALCL by Shadi Ghali / The importance of teamwork and leadership in the management of patients in burns centres by Emily Claire Taylor, Steven LA Jeffery / Focus: Opinions on regulation by Dalvi Humzah, Paul Charlson, Andrew Rankin / CPD certified: Hand rejuvenation with injectable fillers by Medhat Abdelmalek AND MUCH MORE...

Nicotine accelerates diabetes induced retinal changes

This study investigated the influence of nicotine in an experimentally induced diabetic rat model. They used non-invasive high-resolution spectral domain optical coherence tomography (SD-OCT) imaging to provide quantitative information on the temporal alterations of retinal structures at the micrometer resolution...

ANGPTL-4 inhibition reduces inflammation in diabetic retinopathy

Diabetic retinopathy (DR) is the most common cause of blindness in working-age humans, and numbers are rising due to increased cases of type 2 diabetes (T2D). T2D is associated with increased obesity and dyslipidaemia, which is a major risk factor...

Complement Factor H and Factor H-Like protein are expressed in human RPE cells

The role of inflammation in age-related macular degeneration (AMD) is well documented and the association of AMD with the inflammatory marker C-reactive protein (CRP) and members of the complement system underline the role of complements in AMD. Human complement factor...

A pulsatile pump in the TM, a new concept in trabecular outflow research

This is a research article where the authors propose a new model in conceptualising the mechanisms involved in the aqueous outflow at the trabecular meshwork (TM). The authors demonstrated evidence of a pump within the Schlemm’s canal. A pulse generated...

Association between smoking and uveitis

This is a retrospective, population-based, case-control study from the general Kaiser Hawaii population. Over a two year period (1 January 2006 to 31 December 2007), there were 100 confirmed incident cases of uveitis. Two control groups were created, with 522...

Hormonal contraceptives and IIH

This multicentre retrospective population based case control study investigated whether there was a higher incidence of idiopathic intracranial hypertension (IIH) in those patients taking oral contraceptive pills (OCP) and other hormonal contraceptives. Fifty-three women were diagnosed with IIH between Jan...