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Conjunctival lesions in paediatric patients

This article documents the conjunctival lesions in paediatric patients from one unit from 2011–22 inclusive in the UK. There was a total of 85 cases with a mean age presentation of seven years old. Most common lesions were naevi (40%),...

Therapy for limbal stem cell deficiency: cell fate after limbal stem cell transplants

“The beauty of scientific research lies in that the search for answers often yields yet more questions.” A large body of evidence points to the corneoscleral limbal location as the repository of putative epithelial stem cells [1]. Thoft proposed the...

New UK study finds widespread hidden sensory loss

One in four over-50s has vision impairment and three quarters have some hearing loss. Groundbreaking research involving eye tests and hearing examinations with more than 500 over-50’s – the first of its kind in the UK – has revealed widespread...

Risk calculation variability over time in OHT

In this study the authors aimed to assess the variability of the well documented risk model from the Ocular Hypertension Treatment Study (OHTS) that identified higher intraocular pressure (IOP), older age, lower central corneal thickness (CCT), greater vertical cup-to-disc ratio...

IOL power calculation accuracy in childhood cataract surgery

Refractive outcomes in eyes after vitrectomy vary as the timing of cataract surgery may influence the outcome when done as staged surgery after vitreoretinal (VR) surgery or at the same time as VR surgery. The authors aimed to determine the...

Real-world experience and outcomes of SLT laser used as a first-line treatment in ocular hypertension patients in a United Kingdom National Health Service setting

The management of raised intraocular pressure (IOP) in the context of ocular hypertension (OHT) and primary open angle glaucoma (POAG) remains a major contributor to the workload of ophthalmology units across the UK. Treatment of these conditions has historically centred...

Paediatric ophthalmology five-year results of atropine 0.01% efficacy in the myopia control in a European population

This a prospective, randomised and longitudinal study from Madrid, Spain in 361 eyes from 361 children randomised into the control group (177 eyes with no treatment) and the treatment group (184 eyes with 0.01% atropine drops once daily). Complete eye...

Multiple sclerosis and the ocular manifestations

This population study retrospectively identified patients with multiple sclerosis (MS) over a 14-year period. The aim of the study was to report the frequency and severity of ocular conditions associated with MS. Cases were identified from the Rochester Epidemiology Project....

The PMFA Journal - April/May 2019 issue available

FEATURES IN THIS ISSUE: An update on BIA-ALCL by Shadi Ghali / The importance of teamwork and leadership in the management of patients in burns centres by Emily Claire Taylor, Steven LA Jeffery / Focus: Opinions on regulation by Dalvi Humzah, Paul Charlson, Andrew Rankin / CPD certified: Hand rejuvenation with injectable fillers by Medhat Abdelmalek AND MUCH MORE...

Nicotine accelerates diabetes induced retinal changes

This study investigated the influence of nicotine in an experimentally induced diabetic rat model. They used non-invasive high-resolution spectral domain optical coherence tomography (SD-OCT) imaging to provide quantitative information on the temporal alterations of retinal structures at the micrometer resolution...

ANGPTL-4 inhibition reduces inflammation in diabetic retinopathy

Diabetic retinopathy (DR) is the most common cause of blindness in working-age humans, and numbers are rising due to increased cases of type 2 diabetes (T2D). T2D is associated with increased obesity and dyslipidaemia, which is a major risk factor...

Complement Factor H and Factor H-Like protein are expressed in human RPE cells

The role of inflammation in age-related macular degeneration (AMD) is well documented and the association of AMD with the inflammatory marker C-reactive protein (CRP) and members of the complement system underline the role of complements in AMD. Human complement factor...