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Internuclear ophthalmoplegia: a case study
A 44-year-old patient presents with binocular, mostly horizontal diplopia when fixating on moving objects. This has been ongoing for approximately five years. He is known to have multiple sclerosis and had an episode of optic neuritis six years prior in...Profile of a tertiary referral oculoplastics service in the UK
The provision of safe and effective ophthalmic care to large patient populations has always been challenging. Severe restrictions of outpatient clinical activity due to the COVID-19 crisis has compounded this problem, with 26,800 appointments cancelled in our unit in the...
Is exenteration helpful in invasive fungal sinusitis?
Invasive fungal sinusitis is a potentially lethal disease that causes painful orbital apex syndrome with ophthalmoplegia and visual loss. The mechanism of ophthalmoplegia and visual loss is not clear, and neither is the role of radical surgery-orbital exenteration. The authors...
Macular characteristics in unilateral idiopathic FTMH and fellow eyes
This retrospective observational study, conducted at a single site, aimed to compare characteristics of the macular structure and foveal pit in unilateral full-thickness macular hole (FTMH) and healthy fellow eyes. Full-thickness macular holes were further classified into three categories: (1)...Tough gig
‘The times they are a-changin’. The words of this Dylan classic resonate down the decades, and in the light of recent events, speak eloquently to life in 2022. It feels like a lifetime of change has passed since the Eye...It’s easy when you know the rules
As I was travelling along a deserted road on a Sunday last month I saw in my peripheral vision a disconcerting flash of light behind me. Much as I tried to convince myself that the flash was due to the...Renewed momentum in ocular gene and cell therapy, broadening application to chronic disease
Gene and cell therapies offer the prospect of ground-breaking new avenues for the treatment of diseases, reflected in a renewed explosion of interest and investment in retinal gene therapy. Rod McNeil reports recent clinical trial readouts across a diverse range...Ambitions for sustainable service recovery amidst an escalating post-COVID backlog
Rod McNeil reviews plans, activity and solutions to better address the post-COVID backlog and bolster sustainable service recovery. Ophthalmology was the busiest outpatient specialty during the three years to March 2020 across the English NHS and again recorded the highest...
Intravitreal afibercept and ranibizumab for PCV
This is a retrospective, interventional series comprising 98 eyes with polypidal choroidal vasculopathy (PCV) with the aim of comparing treatments with afibercept and ranibizumab, highlighting any differences in their efficacy. Case notes and imaging (FFA / ICG / OCT) were...Retinoblastoma management update (part 2): treatment, screening and surveillance, long-term follow-up and new developments
Retinoblastoma treatment requires significant multidisciplinary input, but early detection through raising awareness remains key to improving outcomes. In the second article of a two-part series, Manoj Parulekar discusses retinoblastoma management, screening and research. This article has been published in two...
