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A comparative treatment study of VCZ and liposomal AmpB in an Aspergillus fumigatus endophthalmitis model

This study aims to compare the effects of voriconazole (VCZ) and liposomal amphotericin B (AmpB) in an experimental model of exogenous Aspergillus fumigatus endophthalmitis in a guinea pig animal model. Endophthalmitis was induced by intravitreal injection of a strain of...

The long-term effects of AREDS on AMD progression

The Age-Related Eye Disease Study (AREDS) was an 11-centre, double-masked, clinical trial that in 2001 found a high-dose of antioxidant vitamins plus zinc was effective in protecting against progression of age-related macular degeneration (AMD) in patients with moderate to high...

Could the sclera be key to glaucoma?

The glaucomas are a group of conditions characterised by optic neuropathy and associated visual field defects. Of these, chronic open-angle glaucoma (COAG) – diagnosed on the basis of progressive structural changes to the optic nerve head (ONH) and nerve fibre...

Invitation issued to world leaders for first-ever Global Summit for Eye Health

Prime Minister Gaston Browne has announced that Antigua and Barbuda will host the first ever Global Summit for Eye Health on 2 November 2026. Announcing the Summit, Prime Minister Browne also extended the invitation to Heads of Government, ministers and...

The COVID-19 ‘frontlines’: a foundation doctor’s perspective

Staring through the fragmented stained glass of the Virgin Mary and her assorted angels, I reflected on the strangeness of the workplace I now found myself working in and the irony of a workforce now working together more enthusiastically than...

Outcomes for strabismus surgery dependent on access to insurance

The primary aim of this study was to compare postoperative outcomes in a larger cohort of paediatric patients having strabismus surgery with at least 11 months follow-up to determine the impact of low socio-economic status (SES) and health disparities and...

Use of botulinum toxin A in the treatment of intermittent exotropia

In this prospective cohort study, the authors aimed to evaluate the efficiency of botulinum toxin A (BTA) injection in the treatment of intermittent exotropia (IXT) and examine factors affecting treatment outcomes. Seventy-four patients diagnosed with any type of IXT were...

Postural control in glaucoma patients with virtual reality

The authors report on a cross-sectional study evaluating postural control and history of falls in glaucoma patients. History of falls was obtained using the Falls Screening and Referral Algorithm. Postural stability was assessed using a force platform under four conditions:...

Emerging developments in dry eye

An estimated 344 million people worldwide suffer from dry eye [1]. This chronic syndrome is characterised by a vicious cycle of tear film hyperosmolarity, tear instability and corneal stress, leading to increased friction, inflammation, ocular surface damage and decreased visual...

Aspirin and upper lid surgery

This is a double-blind randomised controlled trial of preoperative aspirin versus placebo in patients undergoing upper lid blepharoplasty or ptosis surgery. All enrolled patients were already taking aspirin and no other anti-platelet or anticoagulant drugs. All patients either had no...

Glaucoma and erectile dysfunction

In this cross-sectional study with patient questionnaire and retrospective chart review, a total of 167 male patients over 40 years of age were enrolled. Exclusion criteria included previous exposure to radiation and surgical treatment for prostate benign hypertrophy or malignancy....

Blood pressure association with primary open angle glaucoma severity

This prospective observational study involved 47 patients diagnosed with primary open angle glaucoma (POAG) examined to investigate their postural blood pressure response and its potential correlation with the severity of glaucomatous optic neuropathy (GON). Participants underwent intraocular pressure and systemic...