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Eye disease patients have more opportunity than ever to take part in NHS research studies

1 November 2018 | EYE - General
A new report highlights how 76% of UK hospitals now offer patients the opportunity to take part in studies of eye disease to improve research and innovation. ‘Ophthalmology research in the UK’s National Health Service: the structure and performance of...

Comparison of retinal pigment epithelium-choroid graft surgery and anti-VEGF therapy in patients with wet AMD

1 December 2015 | | EYE - Vitreo-Retinal
This was a randomised intervention study in wet AMD patients to investigate benefits of free RPE-choroid graft transplantation surgery versus (continuation of) anti-VEGF treatment. Twenty patients who met the inclusion criteria were subdivided into three subgroups, i.e. RPE tears involving...

Detecting apoptosis in retinal cells

1 February 2022 | | EYE - Vitreo-Retinal | Apoptosis, Glaucoma, Imaging, Neurodegeneration, Retina
This is a review paper in which the authors summarise the transitioning of techniques detecting apoptosis from bench to bedside, along with the future possibilities they encase. Detection of Apoptosis in Retinal Cells (DARC) technology can be used as a...
Ophthalmologica journal cover image.

Effect of syringe-filling technique and risk for endophthalmitis after intravitreal injection of anti-VEGF agents

2 August 2022 | | EYE - Vitreo-Retinal | Aflibercept, Anti-vascular endothelial growth factor, Bevacizumab, Endophthalmitis, Filling, Prefilled syringe, Ranibizumab, Syringe
In this retrospective study the authors compare the risk for post-injection endophthalmitis between different anti-vascular endothelial growth factor (VEGF) agents and syringe preparation technique. This multicentre study included 197,402 injections. The drugs included in this study were three Anti-VEGF agents...

New UK study finds widespread hidden sensory loss

20 October 2025 | The College of Optometrists, funding, eye health, optometry, sensory loss
One in four over-50s has vision impairment and three quarters have some hearing loss. Groundbreaking research involving eye tests and hearing examinations with more than 500 over-50’s – the first of its kind in the UK – has revealed widespread...

Covid-19

23 March 2020 | | EYE - General
I am writing this on 21 March 2020, and I am pretty confident that by the time you read this that whatever I say will already be hopelessly out of date. Plus, it’s only really what I think, and I...

A glossary

5 October 2020 | | EYE - General
After a week on call grading what feels like 13 billion referrals I decided it might be useful to come up with a glossary that might help other people in some way to decipher the true meaning behind every repetitive...

High-stakes scenarios in retinal vein occlusion: A survey of medico-legal implications

2 October 2025 | | EYE - Vitreo-Retinal, EYE - Glaucoma
Central retinal vein occlusion (CRVO) is the second most common retinal vascular disease after diabetic retinopathy, and its clinical complexity often intersects with medico-legal scrutiny [1]. Missteps in timely diagnosis, inadequate follow-up or poor documentation can lead to patient harm...

Behind the eyes: Unravelling the mystery of a painless progressive proptosis

4 February 2025 | | EYE - Oculoplastic, EYE - Orbit, EYE - Pathology
Orbital fungal infections have the potential to give rise to serious complications. While these infections typically originate in the sinuses, patients may initially exhibit ocular symptoms. As a result of the diverse and often vague clinical manifestations (especially during the...

Specialist high-street eye clinics for managing patients with retinal disorders can enhance care standards

1 December 2018 | | EYE - Vitreo-Retinal, EYE - General
The author examines the successful introduction of community-based retinal clinic services by Manchester University NHS Foundation Trust. Dr Sajjad Mahmood, Consultant Ophthalmologist, MREH, shares experience of establishing community-based medical retina clinic services. Sight loss from age-related macular degeneration (AMD), cataract,...

Quiz Aug/Sep 2022

2 August 2022 | EYE - General
History A 58-year-old female patient was referred with a 2-year history, gradually enlarging, painless left upper lid lump. There was no bleeding or ulceration. She had no other eye symptoms and no other skin lesions. Her past medical history included:...

Disseminated cutaneous zoster – a masquerade

1 February 2017 | | EYE - Cornea
Reactivation of varicella zoster infection in the elderly commonly presents to ophthalmologists as herpes zoster ophthalmicus (HZO), affecting the Va trigeminal dermatome. In patients with impaired immunity, zoster infection occurs with increased severity and may be complicated by visceral and...