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Regulatory drug evaluations and expedited review initiatives: EU and US perspectives

The European Medicines Agency (EMA) and United States Food and Drug Administration (FDA) each conduct independent assessments of benefit-risk profile when evaluating applications to market new or modified medicines, and their respective decision-making is guided by distinct legislation, procedures and...

Thyroid eye disease

Thyroid eye disease (TED) is an autoimmune condition with a spectrum of signs and symptoms, usually associated with Graves’ hyperthyroidism. The diagnosis is based on history and physical examination but there are further investigations that can aid diagnosis if unclear....

My Top Five: Foundation year 3 jobs for prospective ophthalmology candidates

Ophthalmology specialist training (OST) is a fantastic career option, however, it is also a highly competitive specialty. There was a gradual rise in competition ratios in recent years: 3.24 (2019), 5.73 (2020), and 6.80 (2021) [1]. Many choose to pursue...

The impact of obstructive sleep apnoea monitoring functionality on smartwatches: a new frontier for ophthalmologists

Dawn of a new era in wearable technology? Smartwatches have really stepped up their game and have evolved from telling time to keeping an eye on our health. In February 2024, the United States Food and Drug Administration (FDA) gave...

The ‘theatre of the mind’: Charles Bonnet Syndrome and Esme’s Umbrella

The founder of Esme’s Umbrella shares her experience with the poorly understood condition Charles Bonnet Syndrome and the creation of the campaign. Many years ago, when I was a young actress, I was in an American play called ‘Butterflies are...

Dropless cataract surgery

Dropless cataract surgery (DCS) describes the complete provision of anti-inflammatory and antibiotic prophylaxis intraoperatively. This eliminates the need for postoperative eyedrops to be self-administered by the patient and thus is also known as ‘dropless after cataract surgery’ (DACS) (n.b. this...

Intraocular surgery and dry eye: Understanding the link, minimising the risk and preparing for the future

Dry eye disease (DED) and ocular surface disease (OSD) are increasingly recognised as central factors in contemporary intraocular surgery. As cataract, glaucoma and vitreoretinal procedures advance toward greater refractive precision, patient expectations have risen and tolerance for postoperative visual fluctuation...

Learnings and trends in the management of open-angle and angle-closure glaucoma

To be truly disruptive, newer technologies need to offer a quality of life benefit over medication to a broad population of glaucoma sufferers. Evidence and converging trends in medical and surgical management of glaucoma were explored in counterpoint discussions and...