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The Lily Foundation celebrates approval of first ever mitochondrial disease treatment by NICE

The Lily Foundation, the UK’s leading mitochondrial disease charity, is today celebrating a landmark achievement in the fight against the disease – the first ever treatment for a mitochondrial condition has been approved for use on the NHS in England....

Bupivicaine injection for Bell’s palsy

This study assesses the use of intramuscular bupivicaine to treat lid retraction and lagophthalmos in facial palsy. It is a prospective non-comparative interventional series of 10 patients with Bell’s palsy (House-Brackman grade IV or V) who each received three serial...

Use of international interocular difference thresholds for optic neuritis diagnosis in clinical practice

Multiple sclerosis (MS) is the most common non-traumatic cause of disability in young people, and visual symptoms can be the initial manifestation in up to 20% of cases. Retinal examination can be helpful in making the correct diagnosis. The latest...

Radiologic characteristics of cavernous venous malformations

This study is a retrospective review of cases with a preoperative radiologic diagnosis of cavernous venous malformations (CVMs) over 30 years. The aim of this study was to define imaging characteristics of CVMs, which will help differentiate these lesions from...

Wide variation in the volume of the sphenoid trigone

This is a radiological study of the volume of the sphenoid trigone in normal subjects. The authors were interested to see how much volume could be gained by removal of the trigone during an orbital decompression for thyroid eye disease....

CFEOM outcomes

This study presents the orbital and cranial magnetic resonance imaging (MRI) findings of patients diagnosed with congenital fibrosis of the extraocular muscles (CFEOM) along with the surgical procedures and outcomes for ocular motility and strabismus. Nine patients are described: three...

Orbital filler for enophthalmos in Parry-Romberg syndrome

This is a retrospective review of three patients with enophthalmos in sighted eyes secondary to Parry-Romberg syndrome. The patients were all female, aged between 24 and 54. All three patients had 4mm of relative enophthalmos prior to treatment. They each...

Radiotherapy for orbital apex cavernous haemangiomas

This is a review of six patients with cavernous venous malformations (haemangiomas) involving the orbital apex who were treated with fractionated stereotactic radiotherapy. Patients were diagnosed on MRI imaging with only one having had previous surgery to debulk the lesion....

Timed resolution of subperiosteal empyema

The purpose of this study was to examine the quantitative changes in subperiosteal empyema (SE) size over time and the time to complete radiographic resolution of this. This was a retrospective case review of 15 cases with orbital cellulitis and...

Mediation of vertical vergence

The authors hypothesised that if vertical vergence were mediated by vertical rectus muscles, then the eye that moves during a vertical fusion task would produce larger vertical vergence when abducted versus adducted. Similarly, if mediated by the oblique muscles then...

Orbital manifestations of granulomatosis with polyangitis

This a retrospective, observational study where authors looked at the ophthalmological examination, biopsy, antibodies and CT scan results of all patients diagnosed with granulomatosis with polyangitis (GPA) from January 2007-January 2019. Out of 101 patients with diagnosis of GPA, 15...

Paediatric emergency presentations in an urban centre

The authors aimed to evaluate aetiologies in paediatric patients presenting to the Wills Eye Emergency department (USA) with particular emphasis on trauma. This was a retrospective review of one-year hospital data; 1136 paediatric patients, 57.4% male, 50.7% white, 36.8% black,...