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RPE atrophy onset in treated nAMD

In this study the authors aim to evaluate the role of various factors for the development of retinal pigment epithelium (RPE) atrophy over a period of five years in patients with nAMD. Fifty-two newly diagnosed nAMD patients with complete absence...

Intravitreal aflibercept for retinal angiomatous proliferation (RAP)

In this prospective study the authors present the visual and anatomical outcome of patients with RAP lesions who were treated with intravitreal aflibercept. The study cohort of 46 patients reached study completion at week 96. They were all Caucasians, with...

Orbital Schwannomas

This is a large case series of orbital Schwannomas managed at a single centre over a 26-year period. Twenty Schwannomas are reported, all but one of which was managed surgically. The tumours were all benign, had an insidious onset and...

Morphological and functional outcome after subthreshold laser coagulation with a frequency-doubled Nd:YAG laser

Central serous chorioretinopathy; Retinal imaging; Retinal laser coagulation

Ocular hypertension following intravitreal steroid injections: a comparative study between triamcinolone-acetonide and dexamethasone-implant

This was a retrospective observational study of steroid response following 1549 intravitreal steroid (TA and Dex) injections. One thousand and seventy-five eyes of 897 patients were reviewed. Glaucoma patients, glaucoma suspects, uveitis, trauma, and cases with less than one month...

Intravitreal Bevacizumab for the prevention of postoperative proliferative vitreoretinopathy in high-risk patients

This single- centre observational retrospective study was conducted to evaluate the effect of intravitreal injection of bevacizumab at the time surgery for rhegmatogenous retinal detachment (RRD) repair on postoperative proliferative vitreoretinopathy (PVR) in patients at high risk selected by laser...

Outcome of secondary intraocular lens implantation-conventional 23- vs. modified 27-gauge vitrectomy port anchor fixation

This retrospective case study series evaluated the outcome of a secondary intraocular lens (IOL) implantation technique of a Carlevale IOL (Soleko IOL Division, Italy) with either a conventional 23- or a modified 27-gauge (-g) vitrectomy port used as anchor fixation....

Autofluorescence patterns in subretinal haemorrhages associated with neovascular age-related macular degeneration

The aim of this retrospective study was to describe the surgical results and fundus autofluorescence (FAF) patterns occurring in sub-macular haemorrhage (SMH) of duration <60 days in age-related macular degeneration (AMD). Notes from 39 eyes of 39 patients with SMH,...

IVTA for diabetic macular edema and macular edema secondary to retinal vein occlusion: a meta-analysis

This meta-analysis aimed to compare the safety and efficacy of different doses of intravitreal triamcinolone acetonide (IVTA) for diabetic macular oedema (DME) and macular oedema (ME) secondary to retinal vein occlusion (RVO). A systematic literature search for randomised controlled trials...

Verteporfin shortage: treatment options and outcomes in chronic non-resolving central serous chorioretinopathy

Half-dose photodynamic therapy (HD-PDT) with verteporfin has been the therapy of choice in non-resolving central serous chorioretinopathy lasting longer than four months. Since 2021, a worldwide shortage of verteporfin due to manufacturing issues prompted adjustments in treatment practices. This retrospective,...

Outcomes in intermediate age-related macular degeneration (AMD): A MACUSTAR study report

Intermediate AMD (iAMD) is the most high-risk AMD stage for progressing to late AMD. This article gives the report of the MACUSTAR study. A wide range of assessments were conducted across 20 sites in seven European countries, in accordance with...