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Outcomes of treated adult-onset ET
This study describes a large cohort of 248 patients with adult onset esotropia (ET) due to a range of causes and details preoperative characteristics, operative procedures and surgical outcomes. Mean age at diagnosis was 52 years. Diagnoses included cranial nerve...
Implantation of diffractive trifocal intraocular lens
This study reports on 60 eyes of 120 patients who underwent routine cataract surgery followed by implantation of the trifocal IOL model Lisa tri-839MP. This is a diffractive trifocal preloaded IOL with no interruption at the haptic-optic junction, 360 degrees...
Intermittent exotropia
Four cases of intermittent exotropia are discussed. Case 1 was a nine-month-old with cycloplegic refraction of +1.0DS and a 30PD intermittent exotropia at near and distance. Discussions considered observation, part-time occlusion, refractive correction and later possibility of surgery. Case 2...
Systematic review of management options for intermittent exotropia
The authors conduct a robust systematic review of the literature to report evidence on non-surgical and surgical treatment options for intermittent exotropia – divergence excess and basic intermittent exotropia types. Discussion centres on (1) optical correction of refractive error with...
Orthokeratology lens treatment for exophoria of convergence insufficiency type
The purpose of this study was to evaluate the effectiveness of orthokeratology (OK) lenses with an increased comparison factor (ICF) of 1.75D in the treatment convergence insufficiency (CI) exophoria (EP). This was a prospective, self-controlled study of 60 eyes (30...Strabismus and ocular motility, demystified
I am a former orthoptist, now trained in medicine and working as a foundation doctor. In my previous work, I was frequently approached by ophthalmology trainees eager for guidance with strabismus and ocular motility. Drawing on my clinical experience, I...Guide to Gaining Approval for a Clinical Study
This article focuses on gaining approval for clinical research involving NHS patients, although the principles can be applied to other types of research. The intention is to give an overview of the requirements for setting up a research study, but...Clinical relevance of the anatomic classification of neovascular age-related macular degeneration
The author explains why an OCT-based classification of neovascular AMD is needed and how these neovascular subtypes may help to predict patients’ long-term visual outcome. Age-related macular degeneration (AMD) is a chronic and progressive neurodegenerative process involving the macula in...
Differential inhibition of EAU by CTLA4 and IL-6
Cytotoxic T lymphocyte antigen-4 (CTLA4) binds both CD80 and Cd86 and inhibits T lymphocyte activation via CD28. Il-6 is a pleiotropic cytokine that has been associated with many autoimmune conditions including uveitis. Blockade of these molecules by either CTLA4-Ig, a...
