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AI predicts eye damage from autoimmune drug, years before symptoms appear

A novel AI tool could transform screening for patients taking hydroxychloroquine by spotting early signs of eye damage, according to a study published in Opthalmology Retina. Researchers have devised an artificial intelligence (AI) system that can detect and predict serious...

PRPF31-related retinitis pigmentosa and asymptomatic carriers

The authors present a study of 21 patients with variants in the PRPF31 gene classified as pathogenic or likely pathogenic. These variants are caused by autosomal dominant retinitis pigmentosa (RP-11). Between January 2020 and November 2021 patients underwent tests of...

Comparison of structural and functional features in primary angle closure and open-angle glaucoma

In this large cross-sectional study, differences in structural and functional damage were assessed among patients with primary open-angle glaucoma (POAG) and primary angle closure glaucoma (PACG) with optical coherence tomography and reliable visual field testing. Two-hundred and eighty-three patients with...

Diary from my elective: a Parisian experience

The author explains how a research institute’s dedication to multidisciplinary collaboration helped him to discover a passion for academic ophthalmology. The elective aspect to the final year of a medical degree, through its change of scenery and immersion into another...

Open source and tele-manufacturing for ophthalmology

Open source or crowd-sourcing and crowd-collaboration are concepts almost always associated with software and public online projects such as Wiki project. Never had I imagined that my team would apply the same principle in ophthalmology. Just less than a month...

Celebrating eight years of the nurse-led intravitreal injection service

Moorfields Eye Hospital NHS Foundation Trust in London celebrated the eighth year of its nurse-led intravitreal (IVT) injection service in 2020. In collaboration with Beaver-Visitec International (BVI), Moorfields’ comprehensive one-day course for non-medical staff has blossomed into a thriving success....

Hospital wins funding to investigate sickle cell sight loss.

The hospital trust is the first in the UK to lead on a research project to understand the impact of sickle cell disease on eyesight.

Update on emerging therapies for age-related macular degeneration

The 23rd European Society of Retina Specialists (EURETINA) Congress, held in Amsterdam, the Netherlands, provided a timely update on anti-complement therapy for geographic atrophy and emerging investigational therapies for neovascular age-related macular degeneration. Anti-complement therapy for geographic atrophy Geographic atrophy...

My Top Five: Red flag presentations all resident doctors must know

Ophthalmic emergencies are time-critical situations where delays in recognition or management can lead to permanent vision loss [1]. For resident doctors and medical students, identifying these red flags can be daunting, especially given the complexity of the eye and its...

AI breakthrough in detecting leading cause of childhood blindness

An artificial intelligence (AI) tool could be an effective way of identifying retinopathy of prematurity (ROP), the leading cause of childhood blindness in middle-income countries, finds a new study led by UCL and Moorfields Eye Hospital researchers.

In conversation with Dr Robert B Nussenblatt

Dr Robert B Nussenblatt is Chief of the Laboratory of Immunology at the National Eye Institute, an eminent ocular immunologist and an expert in clinical research design and conduct. Describe the success or relevance of the SUN project. The Standardization...

Medical malpractice in uveitis: a review of clinical entities and outcomes

This paper presents a retrospective review of malpractice verdicts, rulings and settlements in the United States. Twenty-five cases of uveitis-related litigation spanning 1971-2014 were identified from the database representing 2.3% of all cases. Forty-eight percent of the cases were infectious....