You searched for "melanocytes"
Does a gut-eye axis exist?
1 October 2019
| Simerdip Kaur
|
EYE - General
Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’. Headline: Does a gut-eye axis exist? Over a decade ago, the Human Microbiome Project was launched by...
A closed angle seldom comes alone
1 June 2017
| Lei-Ai Lim
|
EYE - Glaucoma
Case report An 89-year-old lady with dementia was referred to me out of hours by her GP with a few days history of an angry looking left eye for suspected elevated intraocular pressure (IOP). I discovered that this lady first...
Another plant-based remedy for the eye?
Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’. Headline: Another plant-based remedy for the eye? What do the nicknames Mary Jane, tea, and 420 all...Identifying life-threatening uveal melanoma: A directed application of general-purpose AI
Uveal melanoma (UM) is a rare but aggressive eye cancer, affecting approximately six people per million annually [1]. Uveal melanoma arises in three locations: the choroid, ciliary body, and iris. As the most common primary intraocular malignancy in adults, UM...Moorfields: Joint Ocular Oncology and Vitreo Retinal Symposium for Nurses and Ophthalmic Health Care Professionals
15 November 2025
Following the success in 2024 of our first Joint Ocular Oncology and Vitreo Retinal Symposium for Nurses and Ophthalmic Health Care Professionals, we are delighted to announce that the symposium will take place again on 15 November 2025. This unique...
My top five: Trinkets of fact or fiction
3 June 2024
| Nishant Aggarwal
|
EYE - General
Trinkets of adult wisdom are often delivered to children alongside warnings of catastrophic outcomes. In this article we present five ‘facts’ about eye health and vision and ask the question: to what extent are these ideas backed up by literature?...
My Top Five: Trinkets of fact or fiction
3 June 2024
| Nishant Aggarwal
|
EYE - General
Trinkets of adult wisdom are often delivered to children alongside warnings of catastrophic outcomes. In this article we present five ‘facts’ about eye health and vision and ask the question: to what extent are these ideas backed up by literature?...
Aug/Sep 2017 Quiz
History A seven-year-old atopic boy has been treated for phlyctenulosis with mild topical steroids. However, he developed dramatic changes at the right limbus in two weeks. He also had past history of vernal keratoconjunctivitis (VKC) with poor compliance to treatment....
Practice patterns of uveal melanoma management with Iodine-125 brachytherapy
5 August 2020
| Annes Ahmeidat
|
EYE - Pathology, EYE - Oncology
|
Brachytherapy, Treatment practices, Uveal melanoma
With the 2006 Collaborative Ocular Melanoma Study Group (COMS) study demonstrating no difference in survival outcomes for participants randomised to either iodine-125 brachytherapy or enucleation, the majority of primary uveal melanomas in the United States are now treated with brachytherapy....
An update on inherited retinal disorders (part 1) – overview and assessment of inherited retinal disease
1 October 2016
| Michel Michaelides (Prof)
|
EYE - Vitreo-Retinal
Part 2 of this topic can be found here Inherited Retinal Disease (IRD) is the leading cause of blindness certification in the working age population (age 16-64 years) in England and Wales and the second most common in childhood [1]....
PD-1 and retinal ganglion cell death
1 February 2016
| Graham Wallace
|
Apoptosis, Large retinal ganglion cells, Neuroprotection, Optic nerve crush, Programmed cell death-1
Death of retinal ganglion cells (RGC) in conditions like glaucoma leads to permanent visual loss. RGC death can be due to the initial stress such as raised intraocular pressure or secondary to mechanism such as oxidative stress. Programmed cell death-1...
Differential inhibition of EAU by CTLA4 and IL-6
1 February 2016
| Graham Wallace
|
EYE - Vitreo-Retinal
Cytotoxic T lymphocyte antigen-4 (CTLA4) binds both CD80 and Cd86 and inhibits T lymphocyte activation via CD28. Il-6 is a pleiotropic cytokine that has been associated with many autoimmune conditions including uveitis. Blockade of these molecules by either CTLA4-Ig, a...
