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2763 results found

Features of childhood cases of sixth nerve palsy

Based on limited information available for cranial nerve palsies in children, the authors aimed to collect data on new onset paediatric sixth nerve palsies in a UK population. This was a retrospective study over 10 years for children aged <18...

Review of bupivacaine use in treatment of strabismus

This review aimed to assess the applications of bupivacaine (B) in the non-surgical treatment of strabismus in human and animal studies. Animal studies show that singly-innervated fibres with low concentrations of mitochondria and developed sarcoplasmic reticulum are more affected by...

RetCam use in differential diagnosis for retinoblastoma

The authors aimed to evaluate RetCam fundus photography and fluorescein angiography (FA) findings in pseudo retinoblastoma. This was a retrospective review of 36 eyes of 28 patients (of which six were female) with 22 bilateral cases. Mean age at presentation...

Acute comitant esotropia as the presenting sign of diffuse intrinsic pontine glioma

The authors present four children with acute comitant esotropia (AACE) associated with diffuse intrinsic pontine glioma. All were treated with radiation therapy and all subsequently died due to the tumour. Children were aged 5, 5, 4.5 and 11 years. General...

Diagnostic error rates for ROP detection by trainee ophthalmologists

The purpose of this study was to characterise common errors in ROP diagnosis by ophthalmologists-in-training in the USA and Canada. Case acquisition was from a web-based system used for ROP assessment from which 20 cases were selected. Fifty-five trainees from...

Diagnosis and management of paediatric keratoconus

This article reviews the current literature on paediatric keratoconus diagnosis and management. Paediatric cases pose challenges as they may not vocalise unilateral changes, difficulty in obtaining reliable imaging, faster rates of progression, difficultly with contact lenses and presumed worse outcomes...

Posterior circulation stroke associated demographics, risk factors and aetiology

The authors present a retrospective case notes review of patients diagnosed with homonymous hemianopia following a radiologically confirmed stroke. A total of 85 patients were identified by searching an electronic medical records system over an 11-year period. Data were extracted...

Comprehensive review of inherited retinal diseases

The authors offer an up-to-date review of inherited retinal diseases (IRDs). In each section the authors discuss the molecular basis of disease, genotype and clinical manifestation. They also discuss the investigation findings and current evidence in the treatment of the...

Normative reference values for optic nerve sheath diameter in children

The purpose of this study was to measure optic nerve sheath diameter (ONSD) in paediatric patients without pathology using brain CT performed for various reasons and to provide normal tomographic reference values. This was a retrospective study of CT scans...

Longitudinal findings in children with neurofibromatosis type 1

This retrospective chart review evaluates the ophthalmologic findings of children with neurofibromatosis type 1 (NF1). Optic pathway gliomas (OPGs) are the most common tumours found in children with NF1. Findings are compared between eyes with and without optic pathway gliomas...

A novel parameter for angle closure

This is a population cross-sectional study of 464 eyes that underwent swept-source optical coherence tomography (SSOCT) imaging in the dark. Eight out of 128 cross-sectional images were selected for analysis. Matlab was used to measure the iridolenticular contact area (ILCA),...

How the thinking machine is transforming the retinal landscape

Regulatory approval of the first two therapeutic substances for the management of geographic atrophy (GA) secondary to age-related macular degeneration has been a major breakthrough. The authors explored the issue surrounding the lack of agreed therapeutic standards and diagnostic tools...