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Positive diagnosis of acute posterior ischaemic optic nerve neuropathy

Posterior ischaemic optic neuropathy is a rare cause of visual loss believed to be due to infarction in the territory of the pial branches of the ophthalmic artery. There is an absence of clinical signs which means the diagnosis is...

Risk factors for NTG in a young Korean population

Previously known ocular and systemic risk factors for normal tension glaucoma (NTG) include myopia, peripapillary atrophy, disc haemorrhage, migraine, obstructive sleep apnoea, thyroid disease and cerebral infarction. However, most NTG risk factor studies have examined patients aged 40 years and...

Can the angle of origin of the ophthalmic artery predict embolic trajectory?

A retrospective, comparative case-control study was used to test the hypothesis that a risk factor for retinal versus cerebral infarct is the angular origin of the ophthalmic artery from the internal carotid artery. The study compared one group (n=28) who...

Association between smoking and uveitis

This is a retrospective, population-based, case-control study from the general Kaiser Hawaii population. Over a two year period (1 January 2006 to 31 December 2007), there were 100 confirmed incident cases of uveitis. Two control groups were created, with 522...

An atypical presentation of Vogt-Koyanagi-Harada Disease

The authors present a single case of atypical presentation of Vogt-Koyanagi-Harada disease. A 42-year-old female presented with unilateral visual loss associated with systemic symptoms of fever and headache. Initial ophthalmic examination revealed a unilateral neuroretinitis, however, investigations for infectious and...

Medical malpractice in uveitis: a review of clinical entities and outcomes

This paper presents a retrospective review of malpractice verdicts, rulings and settlements in the United States. Twenty-five cases of uveitis-related litigation spanning 1971-2014 were identified from the database representing 2.3% of all cases. Forty-eight percent of the cases were infectious....

The approach to angle-closure glaucoma

Further to my last article in Eye News (print issue) describing the diagnostic approaches to various clinical scenarios in glaucoma, the approach to angle-closure glaucoma (ACG), a situation terrifying for patient and registrar alike, will be discussed. Please refer to...

Treatment of diabetic macular oedema

Diabetic macular oedema (DMO) is a common complication associated with diabetic retinopathy, and the most common cause of visual impairment in diabetes [1]. With predicted rising levels of diabetes (in England by 2025 the estimated population with diabetes will be...

An Inconvenient Truth: Pete’s hidden curriculum Part 4

“What gets us into trouble is not what we don’t know. It’s what we know for sure that just ain’t so.” The above is a quote attributed to Mark Twain from the 2006 documentary, An Inconvenient Truth, which follows Al...

Report: 75th Anniversary of the IOL Gala Dinner

The 29th November 2024 marked the 75th Anniversary of the first intra-ocular lens implant by Sir Harold Ridley who invented the lens in collaboration with John Pike of Rayner. In conjunction with Rayner and UKISCRS, the Ridley Eye Foundation held...

A Multidisciplinary Approach to Neovascular Glaucoma in a Patient with Waldenström’s macroglobulinemia

An 84-year-old Caucasian male attended eye casualty with a four month history of reduced vision, a dull ache and photophobia in both eyes. He had also reported dizziness, weakness and intermittent epistaxis in the nine months prior to presentation. There...

Retinoblastoma chemotherapeutic drugs and their toxic effects on RPE cells

There is reported clinical evidence of retinal pigment epithelium (RPE) alterations after intra-arterial (IAC) and intravitreal chemotherapy (IViC) of retinoblastoma. The purpose of this study was to investigate the cellular toxic effects of melphalan, topotecan and carboplatin on the RPE...