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50 Studies Every Ophthalmologist Should Know

This book features a compilation of 50 important clinical studies that have left a profound impact on the current clinical practice of ophthalmology. From the 1980 botulinum toxin injection study by AB Scott to the United Kingdom Glaucoma Treatment Study...

Ocular electrophysiology

A 34-year-old woman, who is a CEO in a multinational firm, has been losing vision over the last 12 months. She has seen her opticians, who initially tried different glasses but could not improve things. Clinical examination is unremarkable. How...

A career in uveitis

As he retires from clinical practice, the author looks back on his long career in uveitis and how care of these patients has changed dramatically since his days as an undergraduate. My trainees and fellows are often bored by my...

Finasteride and central serous chorioretinopathy

The pathophysiology of central serous chorioretinopathy (CSC) is complex and has not been fully elucidated. Suggested theories include hyperpermeability and increased hydrostatic pressure in the choroidal vasculature, which creates RPE detachments overwhelming the RPE barrier function, leading to accumulation of...

Myopia progression with atropine and different treatment lenses

This study aimed to determine the effectiveness of low dose atropine at inhibiting myopia progression, the possible additive potency of this treatment combined with either of two peripheral defocus contact lenses over three years of therapy, and whether there was...

Can coenzyme Q10 have a protective role in ethambutol-induced retinal ganglion cell toxicity

Tuberculosis (TB) is one of the most prevalent infectious diseases, especially in developing or low- income countries. Ethambutol is a widely used drug to treat TB. Ethambutol can cause visual disturbance including ethambutol toxic optic neuropathy (ETON). ETON is one...

The art of giving generous grains

On the drive home, after a long day of eye screening patients in homeless shelters, I would pass through the boroughs, towns and villages of east London. Stopping at the soup kitchen, I would meet Christian with heavy cataracts, and...

Platelet rich fibrin membrane for descemetocele

This case series described the use of a novel technique in the treatment of descemetocele. Three patients developed descemetoceles following infective keratitis with impending risk of corneal perforation. Platelet rich fibrin (PRF) membrane was prepared using 8ml of fresh venous...

Is pre-eclampsia / eclampsia a risk factor for non-infective uveitis?

This population based retrospective matched cohort study was the first of its kind to suggest an association between preeclampsia / eclampsia (PEE) and non-infective uveitis (NIU). They used the Longitudinal National Health Insurance database in Taiwan to assess 2073 post-delivery...

Environmental variations in endophthalmitis

In this retrospective cohort study, the authors looked at seasonal and environmental variations in 171 endophthalmitis cases out of 423,297 intravitreal injections. The incidence of this complication was not correlated to monthly snowfall, rainfall, or average temperature. There was no...

Assessing possibility of deferring lumbar puncture in mild idiopathic intracranial hypertension

This was a retrospective review of patients consecutively presenting with idiopathic intracranial hypertension (IIH) to a tertiary neuro-ophthalmology clinic without a lumbar puncture (LP) over an eight-year period. Inclusion criteria included true optic disc oedema, retinal nerve layer thickness ≤300µm,...

What's trending Apr/May 2025

A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #ContactLens #Trapped I started wearing contact lenses in my teenage years and was always worried about them slipping behind my eyes....