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My Top Five: Promising gene therapies for ocular conditions

Gene therapy, a pivotal advancement in modern medicine, particularly shines in ophthalmology. By targeting defective genes with engineered vectors, this approach promises significant strides in treating inherited retinal diseases. This article reviews the top five gene therapies in late-stage trials,...

My Top Five: Promising gene therapies for ocular conditions

Gene therapy, a pivotal advancement in modern medicine, particularly shines in ophthalmology. By targeting defective genes with engineered vectors, this approach promises significant strides in treating inherited retinal diseases. This article reviews the top five gene therapies in late-stage trials,...

Autophagy in lens mitochondria loss

The lens consists of a monolayer of epithelial cells that overlies fibre cells that differentiate from epithelial cells at the equator. While developing, fibre cells need mitochondria to provide energy, as they mature they lose these and other organelles to...

Part 1: Her Royal Highness The Duchess of Edinburgh Visits Ethiopia with Orbis

Her Royal Highness The Duchess of Edinburgh, visited services protecting the vision of children and adults in Hawassa, Ethiopia, with international eyecare charity Orbis.

Statins inhibit TGFβ2 mediated fibrotic response in astrocytes

Glaucoma is a common condition where increased ocular pressure can lead to death of retinal ganglion cells due to impaired drainage of fluid from the eye. One mechanism involved in glaucoma is remodelling of the extracellular matrix at the lamina...

Oral proton pump inhibitors in macular degeneration patients

The authors report five patients with advanced wet macular degeneration and poor vision with onset or enhancement of visual hallucinations with the use of proton pump inhibitors for heartburn management. The hallucinations were reversible with discontinuation of medication. The authors...

EyeSi Simulation: a cutting-edge training tool for doctors

As the medical field continues to evolve, so does the need for innovative and effective training methods for doctors. One such advancement in medical education is the EyeSi simulation.

Factors associated with inferior oblique transposition surgery and occurrence of anti-elevation syndrome

The purpose of this study was to correlate the frequency of anti-elevation syndrome (AES) with the magnitude of the anterior transposition of the inferior oblique. This was a retrospective study of 312 eyes of 170 patients. Mean age at surgery...

Review of non-arteritic anterior ischaemic optic neuropathy

This article reviews the risk factors, clinical presentation and therapies that have been investigated for non-arteritic anterior ischaemic optic neuropathy (NAAION). Additionally, it provides an update from recent rodent and primate models, offering a new insight into the pathophysiology of...

Farnborough International Airshow 2022 partners with Orbis UK

Farnborough International Airshow (FIA) announces Orbis UK as its official charity partner for 2022.

The Escape Room and gamification of ophthalmology teaching

Recently, there has been an interesting development in medical education and its ‘gamification’. Educators are constantly looking for new ways to engage their students by adding a friendly element of competition, as evidenced by the great success of online education...

A case of late spontaneous subluxation of in-the-bag intraocular implant

An 82-year-old frail lady was referred by her optometrist with a finding of subluxated implant in the right eye. She had uneventful phacoemulcification with in-the-bag intraocular implant 17 years earlier. There is no history of having had pseudoexfoliation (PXF) or...