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Submacular haemorrhage associated with nAMD: A meta-analysis and meta-regression on use of tPA and anti-VEGFs

The aim of this study was to evaluate the efficacy of a combination of tPA and anti-VEGF in the treatment of submacular haemorrhage (SMH) associated with neovascular age-related macular degeneration (nAMD). A systematic review meta-analysis following PRISMA guidelines, focusing on...

ILM peeling techniques in myopic traction maculopathy

Myopic traction maculopathy (MTM) is a sight-threatening complication of high myopia including macular retinoschisis (MRS) or foveoschisis, foveal detachment (FD) and myopic macular hole (MMH). Standard surgical treatment is vitrectomy with internal limiting membrane (ILM) peeling, but full-thickness macular hole...

Myopia progression with atropine and different treatment lenses

This study aimed to determine the effectiveness of low dose atropine at inhibiting myopia progression, the possible additive potency of this treatment combined with either of two peripheral defocus contact lenses over three years of therapy, and whether there was...

Junior doctors in emergency departments lack confidence when managing ophthalmic emergencies

This systematic review assessed the confidence of doctors in the UK working in emergency departments (EDs) to manage ophthalmic emergencies, with secondary outcomes looking at doctor’s confidence in performing fundoscopy and using the slit-lamp, and training received in the ED....

Beyond ‘Shield and Ship’: a novel device (Eye-Aid) to provide temporary aqueous tamponade

The authors present a pilot efficacy study of the novel Eye-Aid device in a porcine model of full-thickness corneal wounds to mitigate anterior chamber collapse in the forward military environment. Currently, the ‘Shield and Ship’ paradigm taught to military healthcare...

Amblyopia information provided by chatbots – how readable and understandable is this?

The purpose of this study was to evaluate the understandability, actionability and readability of responses to frequently asked questions about amblyopia provided by ChatGPT-3.5, Bing Chat, Bard and the American Association for Pediatric Ophthalmology and Strabismus (AAPOS) website, along with...

Horizontal recti injection of botulinum toxin for treatment of infantile nystagmus

In this study the authors aimed to demonstrate the effect of botulinum toxin (BT) on the frequency of ocular oscillation in children with infantile nystagmus syndrome (INS). Botulinum toxin was administered with direct injection into the horizontal recti muscles using...

Randomised controlled trial of CAM training vs occlusion for amblyopia therapy

The main aim of this study was to compare the effect of Cambridge vision stimulator (CAM) therapy with passive occlusion in the management of unilateral amblyopia. This was an randomised control trial (RCT) with two groups; group 1 with CAM...

Transcriptomic and regulatory gene associations in open angle glaucoma

The authors report a study utilising a publicly available whole exome sequencing dataset of 28 patients with primary open angle glaucoma (POAG) and seven healthy control patients, and a transcriptomic dataset from the trabecular meshwork of four POAG patients and...

Piloting myopic control glasses effects on axial length under mesopic conditions

This study aimed to pilot whether axial length reduces when being treated with myopia control glasses in mesopic conditions. Participants were required to have single-vision glasses with spherical equivalent between -1.00 and -5.00 dioptres, astigmatism less than -1.00 dioptre, a...

Treatment of anisometropia and strabismus amblyopia with syntonic phototherapy

Syntonic phototherapy is a non-invasive light therapy treatment using specific light colours, frequency and wavelength to improve body regulatory centres in the brain. It is proposed that red light increases cell membrane capacitance buildup of electrical charge before discharge that...

Anti-VEGF agents treatment outcomes in macular telangiectasia

This article is a review of a systematic literature search on Ovid MEDLINE, Embase, and Cochrane Library, from inception to June 2024 for comparative studies on anti-VEGF agents in macular telangiectasia (MacTel). The primary outcome was the change in best-corrected...