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1824 results found

Silicone hydrogel contact lenses versus autologous serum drops for dry eyes in Sjörgen syndrome

A total of 37 patients with Sjörgen syndrome (SS) related dry eyes reporting symptoms on standard therapy with artificial tears and anti-inflammatory drops were evaluated in this trial. They were randomly assigned to additional treatment with either balafilcon A silicone...

VKH outcomes with pulse IV steroids

This is a retrospective review of clinical case notes records of 111 Vogt-Koyanagi-Harada (VKH) patients between 1999 and 2015 from a single centre in Tokyo, Japan. The mean age at presentation was 41 years and the median follow-up period was...

Cavernous sinus thrombosis and orbital cellulitis

This is a report of six cases of combined orbital cellulitis and infective cavernous sinus thrombosis, with a literature review. The average age was 39 years, four were male and two were intravenous drug users. All had sinusitis, usually involving...

Quality of life concerns after uveal melanoma diagnosis

The authors sought to investigate factors associated with Quality Of Life (QOL) after initial diagnosis of uveal melanoma (UM) using prospectively collected data between September 2011-May 2016. They included 201 participants referred for radiotherapy after UM diagnosis by an ophthalmic...

Neurofibromatosis type 1 features

The aim in this study was to identify the incidence and de nova mutation rate of Neurofibramatosis type 1 (NF1) and describe the ocular and non-ocular findings in a population-based cohort of patients diagnosed over a 30-year period. The study...

Review of pathogenesis of Acanthamoeba keratitis

In this review, the author summarised the current microbiomic and immunological evidence related to the pathogenesis of Acanthamoeba keratitis (AK). AK has been described for almost 50 years, but the exact biology of the disease remains perplexing. Acanthamoeba spp. are...

OCT choroidal signs for congenital retinal pigment epithelium hypertrophy

Congenital hypertrophy of the retinal pigment epithelium (CHRPE) on ocular coherence tomography (OCT) has the characteristic sign of RPE thickening and hyper reflectivity. However, the underlying choroid characteristics remain under researched. This retrospective study utilised data from an ophthalmic oncology...

Comparing bimedial rectus recession and botulinum toxin for partially accommodative esotropia

The authors present a retrospective case review to compare bimedial rectus recession and botulinum toxin injection to the medial recti. This study was possible due to the different first-line preferences of the individual surgeons within the team. Inclusion criteria were...

Effects of ML4 on the eye

Mucolipidosis type IV (ML4) is an autosomal recessive lysosomal storage disease and is caused by variants of the MC0LN1 gene. It often presents in young individuals with eye and ocular adnexa issues. The authors present a case report and literature...

FEVR characteristics

The authors report a series of 16 cases of familial exudative vitreoretinopathy (FEVR) in Northern Ireland (NI) to characterise the genetic patterns and identify other common characteristics relevant for current and future practice. This was a retrospective study including 12...

Does paediatric rhegmatogenous retinal detachment (RRD) obey Lincoff’s rule (LR)?

This was a retrospective study where 98 paediatric patients with RRD were identified through surgery records. Forty case sheets with complete record of ocular examination and surgical findings were analysed. Visible or suspected preoperative retinal break identified using the LR...

Rare presentation of giant cell arteritis in Chinese subjects

Only a few case reports of biopsy-proven GCA (BpGCA)-associated vision loss in Chinese subjects have been published. This paper presents three elderly Chinese subjects with BpGCA who presented with vision loss. A search of the literature was also conducted to...