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1345 results found

Submacular haemorrhage associated with nAMD: A meta-analysis and meta-regression on use of tPA and anti-VEGFs

The aim of this study was to evaluate the efficacy of a combination of tPA and anti-VEGF in the treatment of submacular haemorrhage (SMH) associated with neovascular age-related macular degeneration (nAMD). A systematic review meta-analysis following PRISMA guidelines, focusing on...

Efficacy of BT as a treatment for cranial nerve palsy in acute and chronic cases

The authors performed a meta-analysis of all patients’ treatment with botulinum toxin (BT) for cranial nerve palsy (CNP) to determine the efficacy of BT in the treatment of CNP due to a variety of causes. The search identified 1129 articles...

Choroideremia in women

The authors report a questionnaire-based study of female carriers of choroideremia, an X-linked inherited chorioretinal dystrophy. As an X-linked condition the full clinical features are predominantly seen in men but a proportion of women suffer some morbidity, likely due to...

Comparison of surgical procedures for third cranial nerve palsy with large-angled exotropia

The authors present a retrospective case review with the aim to compare two surgical procedures. Cases were operated on at a single centre, by a single surgeon, over a 14-year period. The inclusion criteria were cases with congenital or acquired...

Comparison of MRI finding in oculomotor cranial nerve palsies as a result of inflammation and ischaemia

This study aimed to explore the value of asymmetric enhancement of the cavernous sinus on MRI for differential diagnosis between ocular myasthenia gravis, ischemic or inflammatory oculomotor cranial nerve palsies. Three groups were recruited consecutively over a 30-month period and...

Photophobia associated with migraine: Investigating associations with productivity

The aim of this study was to investigate an association between severe photophobia linked to migraine and reduced work productivity. Cases were extracted from the American Registry for Migraine Research (ARMR) with the following criteria: diagnosed with migraine, data available...

Textbook of Community Ophthalmology, 1st Edition

As a medical student with a keen interest in public health, I found Textbook of Community Ophthalmology to be an insightful resource that bridges the gap between individual clinical care and population-based strategies for preventing blindness. The editors present a...

What plane should be used for ultrasound measurement of the optic nerve sheath diameter?

This prospective observational study aimed to evaluate the differences between optic nerve sheath diameter (ONSD) between the patients’ two eyes and different ultrasound planes (transverse and sagittal). Participants were recruited over a two-year period from a single neurosurgical department. To...

Hypothesis for poor visual outcomes in myeline oligodendrocyte glycoprotein-related optic neuritis after first attack

The authors present a retrospective case review with the aim of describing the group of patients with myelin-oligodendrocyte glycoprotein-associated optic neuritis (MOG-ON) who had poor visual outcomes following their first attack despite rapid treatment. The study was conducted at a...

Outline of clinical care for healthy newborns with uncomplicated conjunctivitis in the US

The purpose of this study was to explore the current state of clinical care for healthy newborns with uncomplicated ophthalmia neonatorum (ON) using a large electronic health record dataset. Despite the existence of national guidelines for antepartum screening for N....

Visual acuity improvement in amblyopic eyes following fellow eye vision loss

The authors present a systematic review with the aim of reporting how frequently and to what extent amblyopia recovers following the loss of vision in the fellow eye and identify any potential clinical predictors. Studies including adults with amblyopia and...

Recurrent unilateral preseptal cellulitis secondary to herpes simplex virus infection

Introduction Periorbital (sometimes called preseptal cellulitis) is a common condition which on its own is not normally an ophthalmic or surgical emergency, however it has the potential to cause severe and serious morbidity in cases where the infection has crossed...