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Experimental Eye Research cover image.

Somatostatin protects retinal pericytes

1 April 2018 | | EYE - Vitreo-Retinal
Diabetic retinopathy (DR) is a complication of diabetes, caused by high blood sugar levels damaging the retinal microvasculature. Mechanisms, such as oxidative stress and deposition of advanced glycation end products, leads to glial cell activation and neuronal apoptosis. Pericytes, contractile...
Neuro-Ophthalmology journal cover image

A case presentation of morning glory disc anomaly and peripapillary staphyloma

1 December 2021 | | EYE - Neuro-ophthalmology | Morning glory disc anomaly, amblyopia, contractile staphyloma, esotropia
The purpose of this paper is to present a case of an 18-month-old girl initially presenting with strabismus. Fixation of the affected eye was intermittent with a relative afferent pupillary defect. A fundus photography of the affected left eye showed...
Strabismus journal front cover image.

Comparison of bupivacaine injection vs. mini-tenotomy for small angle deviations

3 June 2024 | | EYE - Paediatrics, EYE - Strabismus
Bupivacaine hydrochloride is an aminoacyltype local anaesthetic. Injection into extraocular muscles elicits a myotoxic response destroying striated muscle fibres but sparing satellite cells, nerves and vessels. Preserved satellite cells proliferate to form new muscle fibres, causing muscle hypertrophy and greater...
Progress in Retinal and Eye Research journal front cover image.

Understanding optic nerve head pericytes and glaucoma

4 December 2025 | | EYE - Glaucoma
The authors provide a comprehensive review of the current understanding of pericytes in the optic nerve head (ONH). Key points include: (1) Pericytes are contractile mural cells that play crucial roles in regulating blood flow, maintaining the blood-brain / blood-retinal...

Ocular bubbly: a vitreoretinal update on the art of gases

5 April 2022 | | EYE - Vitreo-Retinal, EYE - General
The authors remind us of the revolutionary impact gases have had on retinal surgery. In 1938, Rosengren attempted to improve his retina repair surgical outcomes [1]. He discovered that suturing the retina or pressing externally on the sclera were not...

Best way to detect glaucoma progression: by reflecting on the past 25 years

1 June 2018 | | EYE - Glaucoma
Glaucoma – a condition of optic neuropathy leading to progressive visual field loss often associated with raised intraocular pressure. It is fair to say that our definition for this condition has remained unchanged over the last 25 years and the...

Aspiration of anteriorly migrated dexamethasone implant using an 18G intravenous cannula

4 December 2025 | | EYE - Cornea, EYE - Vitreo-Retinal
Intravitreal dexamethasone (Ozurdex 0.7mg) is a biodegradable, sustained-release implant used to manage diabetic macular oedema, macular oedema secondary to retinal vein occlusion, and non-infectious posterior uveitis due to its anti-inflammatory effects and VEGF suppression [1]. While effective, the implant may...

A case of late spontaneous subluxation of in-the-bag intraocular implant

1 April 2017 | | EYE - Cataract, EYE - Refractive
An 82-year-old frail lady was referred by her optometrist with a finding of subluxated implant in the right eye. She had uneventful phacoemulcification with in-the-bag intraocular implant 17 years earlier. There is no history of having had pseudoexfoliation (PXF) or...

The Preston Rule

27 July 2021 | | EYE - General
The selection, specification and fitting of a spectacle frame necessitates the recording of certain measurements particular to the frame. These measurements are also essential when it is required to manufacture a handmade spectacle frame. Instruments designed to accomplish this task...

The management of antiplatelets and anticoagulation in elective ophthalmic surgery

1 April 2016 | | EYE - Orbit, EYE - Oculoplastic
Clinical scenario: A 57-year-old gentleman who is scheduled to have Mohs micrographic surgery and reconstruction for a medial canthal basel cell carcinoma (BCC) has been started on aspirin and clopidogrel following a coronary stent three weeks ago. Does the antiplatelet...

Discussing treatment modalities for bilateral wet AMD

1 December 2014 | | EYE - Vitreo-Retinal
A 65-year-old lady with bilateral wet AMD and vision of 6/24 comes with an internet search about current therapies. How do you explain the various treatment modalities available? There are two NICE approved treatments for wet age-related macular degeneration (AMD)....

Twenty-five years in retina

1 February 2019 | | EYE - Vitreo-Retinal, EYE - General
In the next of our articles celebrating 25 years of Eye News, the authors look at how the retina specialty has changed over this time and ask what the future might hold. Retinal disease management has benefited from great advances...