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Antibiotic prophylaxis after intravitreal injections

The use of topical antibiotics as prophylaxis after intravitreal injections is a contentious issue, especially now with increasing use of intravitreal anti-VEGF agents. In the Wills Eye Institute, prior to May 2011, all patients undergoing intravitreal injections in the office...

Sutureless 27-gauge needle intrascleral intraocular lens implantation

The authors report on a prospective, non-comparative, interventional case series of patients undergoing sutureless intrascleral fixation of a posterior chamber three piece intraocular lens (IOL) using a 27-gauge needle for docking. Sutureless techniques have the advantage of not having complex...

Macular atrophy with aflibercept

The authors of this paper set out to investigate the prevalence of macular atrophy in treatment-naive patients with neovascular AMD undergoing aflibercept monotherapy (three monthly loading injections followed by subsequent treatment every two months). Case notes over a three year...

Disc margin delineation using spectral domain OCT

Observing progressive anatomical changes of the optic nerve head is essential in the detection of progression in glaucoma. Imaging devices continue to evolve and are useful in detecting change in established glaucoma, although probably less useful in an initial diagnosis....

Improving reading of fundus photographs in an emergency setting

The first phases of the FOTO-ED study found that emergency providers perform significantly better with fundus photography than with direct ophthalmoscopy in the detection of fundus abnormalities. The authors hypothesised that by providing additional training to emergency providers, this would...

Can closing the eyelid during riboflavin induction phase of crosslinking increase corneal thickness?

Corneal crosslinking (CXL) with riboflavin and UVA irradiation is the standard treatment for preventing progression of keratoconus. Thinning of the cornea during the riboflavin loading phase was reported in previous studies which used riboflavin with dextran. A minimum stromal thickness...

Quality of life concerns after uveal melanoma diagnosis

The authors sought to investigate factors associated with Quality Of Life (QOL) after initial diagnosis of uveal melanoma (UM) using prospectively collected data between September 2011-May 2016. They included 201 participants referred for radiotherapy after UM diagnosis by an ophthalmic...

OCT angiography sign after whiplash

Berlin’s oedema is a rare condition following blunt ocular injury and a rare finding after whiplash injury. This case describes a 48-year-old male who suffered a seventh vertebrae fracture from a traffic accident. Two days later, decreased left eye visual...

How does low-concentration atropine reduce progression of myopia?

This is a double-blind, randomised, placebo-controlled trial evaluating the effects of low-concentration atropine (0.05%, 0.025%, 0.01%) on ocular biometrics of myopic children. The aim is to determine what aspect of ocular biometrics low-concentration atropine influenced in reducing the progression of...

Tumour deposits following choroidal melanoma treatment

The authors present the unique case of retinoinvasive melanoma following treatment of choroidal melanoma with brachytherapy. Uveal melanoma, the commonest intraocular malignancy in adults, presents as a pigmented mass in the choroid, ciliary body, or iris. A 79-year-old Caucasian male...

Effects of ‘inverted U method’ Nd:YAG laser posterior capsulotomy on anterior segment and IOL tilt

The study aimed to investigate the effects of the ‘inverted U method’ Nd:YAG laser posterior capsulotomy on anterior segment parameters, decentration and tilt of intraocular lens (IOLs) and visual acuity in 76 patients with posterior capsular opacification (PCO) after previous...

Efficacy and safety of novel PF brimonidine / timolol fixed-combination ophthalmic solution for OAG

This study is a multicentre, randomised, open-label, parallel-group clinical trial to evaluate the efficacy and safety of a newly developed preservative-free (PF) brimonidine / timolol fixed-combination (BTFC) ophthalmic solutions as compared with preservative-containing (PC) BTFC ophthalmic solution in adult patients...