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Temporal versus nasal clear corneal incisions

This is a prospective randomised study of 100 patients’ left eye having undergone phacoemulsification either by a 2.4mm nasal clear corneal incision (CCI) group or temporal CCI group. The corneal astigmatic changes were compared between groups by power vector analysis,...

Does amniotic membrane transplant improve outcomes in chemical injuries?

This single centre, randomised, parallel-controlled clinical trial compared the outcomes of patients with Roper-Hall grade IV ocular chemical injury that had conventional treatment vs. combined medical treatment and amniotic membrane transplantation (AMT). They followed up 60 patients between August 2006...

Multimodal imaging in wet AMD

This novel study set out to determine grader agreement levels of various retinal imaging techniques, commonly used in the diagnosis of wet age-related macular degeneration (AMD). Images from 52 eyes were by examined by two different observers. All images were...

VKH outcomes with pulse IV steroids

This is a retrospective review of clinical case notes records of 111 Vogt-Koyanagi-Harada (VKH) patients between 1999 and 2015 from a single centre in Tokyo, Japan. The mean age at presentation was 41 years and the median follow-up period was...

Combined PRK and CXL in keratoconus

This study aimed to investigate the results after photorefractive keratectomy (PRK) followed immediately by standard 30-minute corneal cross-linking (CXL) for keratoconus. This retrospective study included 26 eyes of 16 patients with keratoconus. Uncorrected distance visual acuity (UDVA), corrected distance visual...

Intracameral sodium hyaluronate for postoperative hypotony after Baerveldt glaucoma implant

This is a retrospective study to examine the effect of 0.1ml of sodium intracameral sodium hyaluronate 1.4% (Healon GV – HGV) in patients who had hypotony (IOP<5mmHg) within three months of having a Baerveldt glaucoma implant (BGI) operation. Hypotony is...

Improving reading of fundus photographs in an emergency setting

The first phases of the FOTO-ED study found that emergency providers perform significantly better with fundus photography than with direct ophthalmoscopy in the detection of fundus abnormalities. The authors hypothesised that by providing additional training to emergency providers, this would...

Can closing the eyelid during riboflavin induction phase of crosslinking increase corneal thickness?

Corneal crosslinking (CXL) with riboflavin and UVA irradiation is the standard treatment for preventing progression of keratoconus. Thinning of the cornea during the riboflavin loading phase was reported in previous studies which used riboflavin with dextran. A minimum stromal thickness...

Atrophy and anti-VEGF

The aim of this study was to investigate treatment factors, along with ocular and systemic factors for their association with macular atrophy (MA) incidence in eyes with neovascular age-related macular degeneration (nAMD) treated with anti-VEGF aflibercept or ranibizumab according to...

Subthreshold micropulse laser in BRVO

The purpose of this retrospective, consecutive, single-centre, non-randomised, and case-control study was to verify the therapeutic effects and safety of oedema (from branch retinal vein occlusion (BRVO)) recurrence suppression effect using 577-nm subthreshold micropulse laser photocoagulation (SMLP) in combination with...

Mini DMEK for acute hydrops

This is a retrospective analysis of three patients who underwent mini DMEK for massive corneal hydrops in acute keratoconus. DMEK graft was trephined or trimmed according to the size and the shape of the gap in the patient’s Descemet membrane...

Injection of methotrexate into silicone oil-filled eyes for grade C PVR

Methotrexate (MTX) is an antineoplastic antimetabolite with immunosuppressant properties. Folate antagonism is known to contribute to the antiproliferative effects of MTX, and release of adenosine from cells and inhibition of polyamines may explain its anti-inflammatory effects. These activities contribute to...