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4714 results found

Effect of long-term scleral contact lenses on corneal topography, tear film and impression cytology in keratoconus

This study of 16 keratoconus patients aimed to investigate the impact of long-term scleral contact lens (ScCL) wear on corneal curvature, corneal thickness, tear film function and ocular surface in patients with keratoconus. Corneal topography, tear osmolarity test, Schirmer 1...

Detection of post stroke visual impairment in variety of cohorts

The Impact of Visual Impairment after Stroke (IVIS) study introduced a standardised vision assessment protocol across three acute stroke units in the northwest of England, with a similar demographic population (predominantly white British). The study reported similar rates of visual...

Can retinal layer thickness predict the progression of disability in MS?

This is an observational retrospective cohort study presenting the data of 188 patient diagnoses with multiple sclerosis at two specialist centres. All included patients were adults below the age of 70 years, stable on their disease modifying treatment for at...

OCT biomarkers in asymmetric anti-VEGF response in bilateral diabetic macular oedema

This study aimed to identify optical coherence tomography (OCT) biomarkers for predicting response to anti-VEGF treatment in diabetic macular oedema (DMO). Bilateral DMO patients with asymmetric response to a loading dose of anti-VEGF (ranibizumab / aflibercept) treatment were retrospectively studied....

Does lower eyelid entropion repair alter corneal topography?

The authors aimed to analyse the corneal morphology before and after advancement of posterior lower eyelid retractors (LERs) alone or in combination with a lateral tarsal strip (LTS) for lower eyelid involutional entropion. Retrospective analysis of 24 consecutive elderly patients...

Frontalis muscle flap for congenital ptosis

This is a review of 43 patients (47 eyes) with severe congenital ptosis who underwent a suspension procedure using a frontalis flap technique. The average age of patients was 6 +/-2.5 years, and all had a severe ptosis with an...

Diplopia after orbital decompression

This is a review of patients undergoing a balanced two-wall and fat orbital decompression to identify risk factors for new onset diplopia. Standard decompression techniques were used, but as the surgery was conducted by ENT surgeons, the medial walls were...

Use of pattern-reversal VEP in congenital Zika syndrome (CZS) assessment

The authors conducted pattern reversal visual evoked potential (PRVEP) in children with congenital Zika syndrome (CZS) and report the correlates with visual acuity, fundus alterations and severity of microcephaly at birth. This was a cross-sectional study of 37 children with...

Inflammation and microvascular changes in diabetic retinopathy

Studies have shown that neurodegeneration and inflammation in the retina start early in diabetic retinopathy (DR) and can be present before the latter is clinically evident. The aim of this retrospective review of 99 diabetic patients was to evaluate retinal...

Corectopia grading

The authors present a novel corectopia classification system using 28 eyes of 28 patients with or without corectopia. The grading and classification system for corectopia was as follows: (i) Direction of decentration: superior (DecS), superonasal (DecSN), nasal (DecN), inferonasal (DecIN),...

Effects of market competition on the price of topical eye drops in the US

The authors retrospectively examined the relationship between the number of Federal Drug Administration (FDA)-approved manufacturers and the price change of generic and branded topical eye medications based on the formulations listed in the FDA Orange Book and the National Average...

Lamellar patch grafts utilising cornea remnants from DMEK/PKP

The authors retrospectively reviewed 23 lamellar patch grafts performed over a six-year period for tectonic indications in corneal thinning and perforations. The anterior stroma of corneal endothelium peeled for descemet membrane endothelial keratoplasty (DMEK) were used to prepare circular lamellar...