Search

Enzymatic clearance of anterior chamber infiltrate in uveitis

Aqueous humour (AH) which fills the anterior chamber (AC) of the eye provides nutrients to the cornea and the lens. Clearance of cellular and particular matter from AH is necessary for good visual acuity. In part this is achieved by...

Swept source anterior segment OCT

The authors describe a study using the Casia OCT which is a swept source OCT to determine the visibility of the angle structures using two imaging protocols; high density and low density. They randomly selected one eye from 30 normal...

Retinal changes prior to hydroxychloroquine toxicity

In this retrospective longitudinal study, the authors examined changes in retinal layer thickness in patients taking hydroxychloroquine without evidence of retinopathy. Patients were drawn from a hydroxychloroquine screening clinic and required at least two OCT scans, at least one year...

Paediatric emergency presentations in an urban centre

The authors aimed to evaluate aetiologies in paediatric patients presenting to the Wills Eye Emergency department (USA) with particular emphasis on trauma. This was a retrospective review of one-year hospital data; 1136 paediatric patients, 57.4% male, 50.7% white, 36.8% black,...

Environmental variations in endophthalmitis

In this retrospective cohort study, the authors looked at seasonal and environmental variations in 171 endophthalmitis cases out of 423,297 intravitreal injections. The incidence of this complication was not correlated to monthly snowfall, rainfall, or average temperature. There was no...

Myopia in Han Chinese

The authors present a case-control study of 361 patients with high myopia (mean spherical equivalent of -6.0DS or lower, and axial length greater than or equal to 26mm) and 749 healthy controls (mean spherical equivalent -1.0 to +1.0DS). They tested...

Progression of macular atrophy in Stargardt disease

The authors present a study of a cohort of patients with genetically proven ABCA4 gene mutation related Stargardt disease. They aimed to quantify the effect of lesion location and topography on disease progression using fundus autofluorescence imaging. One hundred and...

Adjunct amniotic membrane during enucleation for retinoblastoma to prevent implant exposure

Amniotic membrane (AM) has potential for treatment of retinoblastoma (RB) patients with contracted sockets after enucleation. The authors present their experience of AM with enucleation for patients with RB after chemotherapy in this retrospective study of 100 eyes of 107...

Ethnic variation in strabismus patterns in Down syndrome

The authors present a systematic review and meta-analysis evaluating the prevalence and aetiology of strabismus in individuals with Down syndrome, with particular focus on ethnic variation in the esotropia to exotropia ratio. Data from multiple studies across diverse populations were...

Limitations of next generation sequencing

This is a report of a young female patient with clinically diagnosed retinitis pigmentosa who underwent genetic testing using an inherited retinal disease panel and whole exome sequencing by next generation sequencing (NGS) technology. This approach did not identify any...