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Guide to Gaining Approval for a Clinical Study
This article focuses on gaining approval for clinical research involving NHS patients, although the principles can be applied to other types of research. The intention is to give an overview of the requirements for setting up a research study, but...Evidence shows hand-holding volunteers help significantly reduce anxiety for patients undergoing eye procedure
New evidence from an evaluation carried out by Helpforce for Friends of Moorfields shows that a volunteer’s support can help patients while they have eye surgery under local anaesthetic. 94% say the support helped them feel less anxious.
Online tool for converting finger counting acuity into Snellen equivalent
The authors describe an online tool which has the purpose of converting count finger measurements of visual acuity into Snellen equivalents. The purpose of this is to allow the re-interpretation of retrospectively collected data that provide visual acuity in this...Scottish stories come to life in audio
Scottish Book Trust has partnered with national sight loss charity RNIB to produce an accessible audio edition of Book Week Scotland’s free book, ahead of this year’s event, which ran ahead of Book Week Scotland (17–23 November 2025). This year’s...Origami and ophthalmology: precision unfolded
For Eye News Feb/Mar 2024, I was delighted to hear from Dr Hosam Aglan. In New Zealand at the time, Dr Aglan shared wonderful insights into the art of folding origami, along with images from his own creations. The role...
Suspected vitreous seeding of uveal melanoma
This is a retrospective non-randomised study of 23 patients with consecutive uveal melanoma who underwent diagnostic vitrectomy between the period of January 2000 and November 2013. The reason for vitrectomy was suspected dissemination of tumour cells inside the eye. The...
Differential inhibition of EAU by CTLA4 and IL-6
Cytotoxic T lymphocyte antigen-4 (CTLA4) binds both CD80 and Cd86 and inhibits T lymphocyte activation via CD28. Il-6 is a pleiotropic cytokine that has been associated with many autoimmune conditions including uveitis. Blockade of these molecules by either CTLA4-Ig, a...
The effect of caffeine on pupil size and accommodation
Twenty-two young and healthy participants were recruited in this study. The authors showed that pupil size increased as a result of caffeine consumption. A more stable (lower variability of accommodation) accommodative response (AR) was induced by caffeine intake, whereas the...
