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Autophagy in lens mitochondria loss

The lens consists of a monolayer of epithelial cells that overlies fibre cells that differentiate from epithelial cells at the equator. While developing, fibre cells need mitochondria to provide energy, as they mature they lose these and other organelles to...

Prism adaptation test in acquired non-accommodative esotropia

This study investigated factors related to the increase in prism adapted angle in patients with acquired non-accommodative comitant esotropia (ANAET) who had strabismus surgery based on the results of a short prism adaptation test (PAT) and evaluated their outcomes. Short...

Breakthroughs in the genetics of angle-closure glaucoma

Angle closure glaucoma (ACG) is not widely known to be a familial condition, yet the recent explosion of genetic data and large scale genome wide investigations have confirmed at least 13 genetic loci associated with ACG [1], and provided some...

More sensitive visual acuity test for age-related macular degeneration

Age-related macular degeneration (AMD) is the leading cause of blindness in the developed world. Primarily associated with ageing, genetic factors and lifestyle choices such as smoking also play a contributory role. Patients with early AMD, characterised by the development of...

Management of traumatic corneal perforations with anterior lamellar techniques: The mini-DSAEK

The authors present the first case report in which a mini (reduced diameter) Descemet’s stripping automated endothelial keratoplasty (mini-DSAEK) has been used to manage a traumatic corneal perforation. A 69-year-old male presented with 6/36 best spectacle-corrected visual acuity (BSCVA) and...

Patient safety – is this achieved in optometry with CET?

Collecting points and ticking boxes – as we come to the end of another three year cycle of continuing education and training (CET), the rush to ensure that everything has been completed on the myGOC (General Optical Council) dashboard feels...

Rotational stability of angle supported phakic IOL

The authors evaluate 50 eyes of 28 patients that underwent an angle fixated phakic intraocular lens (IOL) implantation (Acrysof Cachet). All eyes had moderate to high myopia (-5.25 to-19.63 dioptres) and IOL sizing was performed as per the manufacturer’s recommendation....

Closed-chamber haptic re-externalisation for posteriorly displaced sclerotomy and inadequate haptic tuck in glued posterior chamber intraocular lenses

This technique (online video http://jcrsjournal.org) emphasises the importance of both symmetrical and sufficient anterior placement of sclerotomies to externalise an adequate length of the haptics, which in turn provides good centration and stability of the intra-ocular lens (IOL). The authors...

William’s syndrome

William’s syndrome is a congenital multisystem disorder involving the cardiovascular, connective tissue and central nervous systems. The aim of this study was to evaluate the frequency and severity of ophthalmic manifestations and associated diseases as well as provide epidemiology data...

Two bifocals and a trifocal

The authors compare the optical outcomes of two bifocal intraocular lenses (AcrySof ReSTOR +2.50 Diopter [D] add +3.0D add) with a trifocal lens (AT LISA tri 839MP). The optical qualities of the lenses were quantified by measuring the modulation transfer...

Using graphical illustration to predict giant cell arteritis

A nomogram is a chart or graph of scaled variables that facilitates the approximate computation of a mathematical function via intersecting lines. The objective of this study was to illustrate the use of a nomogram for the prediction of giant...

EyeLogbook

This issue we’re covering the recently updated EyeLogbook (www.eyelogbook.co.uk), the Royal College of Ophthalmologist’s (RCO) online surgical logbook. Back in March 2016 a fully re-designed version of the site was released. Not only does the new version bring a beautifully...