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Long-standing flattening effects on the globe following spaceflight

Posterior globe flattening has been well-documented in astronauts both during and after long-duration spaceflight (LDSF). This globe flattening is thought to be due to the disc centred anterior forces created by elevated volume and / or pressure within the optic...

Case presentation: seizures as a presenting sign of idiopathic intracranial hypertension

Idiopathic intracranial hypertension (IIH) is a syndrome of isolated elevated intracranial pressure of unknown cause. Neurological examination in IIH is typically normal except for papilloedema and possible cranial nerve six palsy, although rare, atypical symptoms and signs can occur. With...

Understanding optic nerve head pericytes and glaucoma

The authors provide a comprehensive review of the current understanding of pericytes in the optic nerve head (ONH). Key points include: (1) Pericytes are contractile mural cells that play crucial roles in regulating blood flow, maintaining the blood-brain / blood-retinal...

Revolutionising eyecare: Gloucestershire’s Community Ophthalmic Link delivers nationally significant results

Ophthalmology is the largest outpatient specialty in the NHS, and in Gloucestershire, it is growing at an annual rate of 2.55%, outpacing other specialties. However, rising demand has led to significant waiting lists, often resulting in patients not being seen...

The David J Apple International Laboratory for Ocular Pathology – a legacy of pioneering IOL research

David Apple and Gerd Auffarth. The Apple Lab at the David J Apple Center for Vision Research in Heidelberg is a thriving international laboratory for research into intraocular devices. The lab continues the work of David J Apple, a world-renowned...

RCOphth Manual Small Incision Cataract Surgery - April 26

The Royal College of Ophthalmologists Manual Small Incision Cataract Surgery Course

RCOphth Manual Small Incision Cataract Surgery Apr 26

The Royal College of Ophthalmologists Manual Small Incision Cataract Surgery

RCOphth (The Royal College of Ophthalmologists) Manual Small Incision Cataract Surgery

This one day intense simulation-based surgical training course for manual small incision cataract surgery covers all the crucial steps needed for competence in a cataract procedure which is safe, suitable and sutureless for mature and brunescent cataracts. It is the...

Use of pattern-reversal VEP in congenital Zika syndrome (CZS) assessment

The authors conducted pattern reversal visual evoked potential (PRVEP) in children with congenital Zika syndrome (CZS) and report the correlates with visual acuity, fundus alterations and severity of microcephaly at birth. This was a cross-sectional study of 37 children with...

Ocular manifestations of multiple sclerosis: an overview

Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system (CNS), in which there is dissemination of lesions in time (two or more clinical events) and space (multiple lesions seen on brain and spinal imaging). The pathophysiology...

Aspiration of anteriorly migrated dexamethasone implant using an 18G intravenous cannula

Intravitreal dexamethasone (Ozurdex 0.7mg) is a biodegradable, sustained-release implant used to manage diabetic macular oedema, macular oedema secondary to retinal vein occlusion, and non-infectious posterior uveitis due to its anti-inflammatory effects and VEGF suppression [1]. While effective, the implant may...

Conference Report: RCOphth 2025

This year’s Royal College of Ophthalmologists Annual Congress in Liverpool brought together eyecare professionals from across the country and beyond for four days of thought-provoking content, collaborative discussion and exciting glimpses into the future of ophthalmology. The opening day was...