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Effect of change in retinal nerve fibre layer thickness on quality of life in patients with glaucoma

The authors investigated the relationship between structural changes in glaucoma (retinal nerve fibre layer (RNFL) thickness) and quality of life (as measured by the NEI VFQ-25 questionnaire) over a period of time. Two hundred and sixty eyes of 130 patients...

Biodegradable plates in lateral orbitotomy surgery

This is a description of a new method for fixating the bone flap during a lateral orbitotomy. The technique involves the use of an absorbable lactide plate. This is warmed in a water bath to allow trimming and moulding to...

Expert vs. non expert grading of ROP from digital video images

The primary purpose of this study was to determine whether digital video images of the retina obtained using an indirect ophthalmoscope imaging system could be accurately graded for zone and stage of retinopathy of prematurity (ROP) and the presence of...

Smartphone based visual acuity

Smartphone technology is becoming widely available to all age groups and settings. Apps using Snellen acuity charts are widely available and this study evaluated the equivalence of a smartphone-based visual acuity chart with a standard 6m Snellen visual acuity (6SVA)...

Exposure to atomic bomb radiation and age-related macular degeneration in later life

This paper is one of the outcomes of the Adult Health Study; a cohort study of the atomic bomb survivors of Hiroshima-Nagasaki in Japan. It investigates the proposed association between pasty radiation exposure early in life and the presence of...

Analysis of risk factors for intraocular pressure rise following insertion of fluocinolone acetonide injection in uveitic patients

For this study, the authors analysed the pooled data from three phase2b / 3 multi-centre randomised controlled trials carried out over three years. Included patients had undergone at least one of the following treatments: 1) systemic therapy (corticosteroid / immunosuppressant...

Intensive diabetes therapy and ocular surgery in type 1 diabetes

The Diabetes Control and Complications Trial (DCCT) ran between 1983 and 1993 and showed that intensive glycaemic control was beneficial in reducing diabetic retinopathy in type 1 patients. There was a 76% reduction in onset of retinopathy and a 52%...

Long-term effect of gene therapy on Leber’s congenital amaurosis

After reporting the first successful gene therapy results for RPE65 deficiency in three patients in a brief report in 2008, the same team from London now report the results of 12 patients followed up for three years after transfection. As...

Inner nuclear layer of the retina showing increase in thickness in diabetic macular oedema

Diabetic retinopathy is one of the leading causes of blindness in the developed world. With optical coherence tomography (OCT), it has become possible to image the retina in vivo and to measure retinal oedema by measuring retinal thickness (RT) with...

Mid-term evaluation of the new Glaukos iStent

This is a prospective non-randomised interventional study to assess the efficacy and safety of the Glaukos GTS-400 iStent combined with cataract surgery. The patients enrolled in the study had cataract and primary open angle glaucoma, pseudoexfoliation glaucoma or ocular hypertension....

Secondary intraocular lens implantation in children

This is a retrospective study of the medical records of children under the age of 16 who underwent secondary lens implantation for aphakic corrections after previous congenital cataract surgery over a period between January 2000 and December 2010. The study...

Mitomycin C versus 5-FU as an adjunctive treatment for trabeculectomy

Antifibrotic agents are used during trabeculectomy (TRAB) to improve long-term surgical success by reducing fibrosis of subconjunctival and episcleral tissue. The purpose of this meta-analysis was to directly compare the efficacy and safety of the two most frequently used antifibrotic...