You searched for "inflammation"
Serology testing in periocular inflammatory disease
This is a review article of serological tests in thyroid eye disease, IgG4-related disease and myasthenia gravis. The authors provide an overview of the current serology with a brief description of how they relate to the pathogenesis of each condition....Effect of topical diclofenac on postoperative PRK pain: RCT
1 April 2015
| Anjali Gupta
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EYE - Cornea, EYE - General
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cornea, diclofenac, pain, photorefractive keratectomy
A major disadvantage of excimer laser photorefractive keratectomy (PRK) is pain and discomfort after the surgery, which is thought to be due to damage to corneal sensory nerve fibres or local release of inflammatory substances. Pain only resolves once corneal...
Inhibiting high-risk corneal allografts
1 October 2014
| Graham Wallace
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EYE - Cornea, EYE - General
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T regulatory cells, Tim-1, high-risk corneal allograft rejection, mice
The cornea is an immune privileged site and as such corneal transplants are very successful. However, in situations where this privilege is lost the failure rises substantially. To combat rejection inhibition of the immune responses depends on steroids and other...
Injection of methotrexate into silicone oil-filled eyes for grade C PVR
1 October 2019
| Sofia Rokerya
|
EYE - Vitreo-Retinal
Methotrexate (MTX) is an antineoplastic antimetabolite with immunosuppressant properties. Folate antagonism is known to contribute to the antiproliferative effects of MTX, and release of adenosine from cells and inhibition of polyamines may explain its anti-inflammatory effects. These activities contribute to...
Pain control during orbital implant surgery
This is a study based on existing evidence that pre-emptive pain control has advantages over traditional post-surgical analgesia. The authors compared pain scores in three groups of randomly assigned and masked patients all undergoing orbital implant surgery under general anaesthesia...Long-term results of cross-linking treatment for keratoconus
The authors report on the long-term outcomes in a prospective case series of patients with keratoconus undergoing corneal collagen cross-linking (CXL) treatment. Thirty-two patients (40 eyes; mean age 22.5+/-5.5 years) with Grade I, II and III progressive keratoconus were recruited...Effects of ML4 on the eye
Mucolipidosis type IV (ML4) is an autosomal recessive lysosomal storage disease and is caused by variants of the MC0LN1 gene. It often presents in young individuals with eye and ocular adnexa issues. The authors present a case report and literature...RCOphth (The Royal College of Ophthalmologists) Cataract Surgery Complications
31 October 2024
This course will focus on the practical management of posterior capsule rupture and zonular dialysis. This will be a “hands on” course with the emphasis on practicing anterior vitrectomy techniques, the use of capsular tension rings, capsule hooks and sulcus IOL implantation. There will also be interactive small group teaching on how to prevent surgical complications during phacoemulsification surgery. The course is aimed at ST5-ST7 trainees, Fellows and Consultants.