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3491 results found

Renewed momentum in ocular gene and cell therapy, broadening application to chronic disease

Gene and cell therapies offer the prospect of ground-breaking new avenues for the treatment of diseases, reflected in a renewed explosion of interest and investment in retinal gene therapy. Rod McNeil reports recent clinical trial readouts across a diverse range...

Aug/Sep 2015 Quiz 2

History A two-year-old female child presented with loss of vision in her left eye. Examination showed leukocoria and intraocular calcification was identified on scanning. The suspected diagnosis was intraocular retinoblastoma and the child underwent an enucleation. The eyeball was submitted...

Using optical coherence tomography angiography to detect MoyaMoya vasculopathy

Moyamoya (MM) disease is a chronic cerebrovascular disease that can lead to progressive stenosis of the terminal portions of the internal carotid arteries and their proximal branches. The authors carried out a cross-sectional cohort study to investigate vascular changes in...

Occurrence and risk factors for RD after PPV in acute postcataract bacterial endophthalmitis

This is a prospective multicentre study from France between March 2004 to December 2011 in four university hospitals; 123 consecutive patients treated with pars planar vitrectomy (PPV) were included in this cohort. The rate of retinal detachment (RD) of post-PPV...

Laser pointer maculopathy

The objective of this study was to describe the potential clinical presentations of retinal pathology resulting from exposure to laser pointers. The study included eight eyes of seven patients. Mean age was 18.7 years (12-36). Most were accidental self-inflicted while...

Ultra-widefield fundus autofluorescence

The authors assessed the ease and utility of ultra-widefield fundus autofluorescence (UWF-FAF) in detecting suspected inherited retinal disease in children who were difficult to examine. They aimed to assess the sensitivity of UWF-FAF and UWF-CF (colour fundus) photography and clinical...

Cataract extraction and microperimetry

In this study, the authors assessed retinal sensitivity before and after cataract extraction, in an effort to understand how lens opacities may affect microperimetry results in glaucoma and macular diseases. Thirty patients awaiting cataract extraction were examined and their lens...

Visual outcomes after surgery for primary RRD in era of microincision vitrectomy

This is a prospective, multicentre, nationwide study between 2016 and 2017, to investigate the preoperative ocular factors, surgical techniques (pars plana vitrectomy (PPV) or scleral buckling (SB), or combined procedures) for rhegmatogenous retinal detachment (RRD) and postoperative best corrected visual...

Covid-19 ophthalmopathy

Ocular involvement is not uncommon in patients with Covid-19. However, the incidence of Covid-19 ophthalmopathy is unclear. The authors present a prospective case series including 2445 consecutive cases presenting at a neuro-ophthalmology clinic during the last resurgence of SARS-CoV-2 infection....

OCT use with macular retinoblastoma

The authors explore the use of portable hand-held spectral domain OCT (SD-OCT) in three eyes of three infants and young children with macular retinoblastoma. All were treated with chemotherapy and all had SD-OCT before and after treatment. The children were...

Traumatic injuries from foam Nerf bullets

Background Three patients are presented in this case report: an adult and two children which were subjected to ocular injuries from Nerf gun bullets. Generally, Nerf guns are considered safer than airsoft guns. While there are many papers on airsoft...

Age-related macular degeneration in elderly persons in Germany

The authors present the findings of a cross-sectional study in 11 seniors’ community centres. Eleven community centres were screened with a total of 281 participants. A third of participants with gradable images were in normal retinal health (32%).The most common...