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Sclerotomy suturing
This was a retrospective review of 589 consecutive cases of patients who underwent 23-gauge tranconjunctival pars plana vitrectomy. Cases were split into Type 1 vitrectomies (macular hole, ERM and simple vitreous haemorrhages) and Type 2 cases which were more complex...
Antibiotic prophylaxis after intravitreal injections
The use of topical antibiotics as prophylaxis after intravitreal injections is a contentious issue, especially now with increasing use of intravitreal anti-VEGF agents. In the Wills Eye Institute, prior to May 2011, all patients undergoing intravitreal injections in the office...
PERG as a visual prognosticator in chiasmatic tumours
Pattern electroretinogram (PERG) allows assessment of ganglion cell function and may therefore be used to assess anterior visual pathway dysfunction. This prospective non-randomised study assessed PERG before and after surgical removal of tumours in and around the sellar region compressing...
PRN Ranibizumab verses continuous aflibercept in UK clinical practice
This was a multicentre (21 UK hospitals), national EMR study on treatment naïve nAMD eyes, undergoing predominantly as needed (PRN) Ranibizumab or continuous (fixed or treat and extend - (F/TE)) Aflibercept (Af). The primary outcome was change in vision at...
Exposure to atomic bomb radiation and age-related macular degeneration in later life
This paper is one of the outcomes of the Adult Health Study; a cohort study of the atomic bomb survivors of Hiroshima-Nagasaki in Japan. It investigates the proposed association between pasty radiation exposure early in life and the presence of...
Combined anti-VEGF and PDT for wet AMD
The authors report on a retrospective case series of combined anti-VEGF and photodynamic therapy (PDT) in the treatment of wet age-related macular degeneration (AMD) refractory to anti-VEGF monotherapy alone. The criteria for treatment failure of anti-VEGF monotherapy were persistent subretinal...
Disc margin delineation using spectral domain OCT
Observing progressive anatomical changes of the optic nerve head is essential in the detection of progression in glaucoma. Imaging devices continue to evolve and are useful in detecting change in established glaucoma, although probably less useful in an initial diagnosis....
Delayed improvement in Muller’s muscle ptosis surgery
This is a retrospective review of patients undergoing ptosis surgery. The authors had noticed anecdotally that although a posterior approach Muller’s muscle and conjunctival resection (MMCR) appeared to achieve similar results to an anterior approach levator resection (ALR) in the...
Type 3 CNV and anti-VEGF
The purpose of the study was to determine the differences between aflibercept and ranibizumab in terms of their therapeutic efficacy in the treatment of Type 3 neovascularisation. The authors highlight that the dominant mechanism for Type 3 neovascularisation development is...
Temporal versus nasal clear corneal incisions
This is a prospective randomised study of 100 patients’ left eye having undergone phacoemulsification either by a 2.4mm nasal clear corneal incision (CCI) group or temporal CCI group. The corneal astigmatic changes were compared between groups by power vector analysis,...
Improving reading of fundus photographs in an emergency setting
The first phases of the FOTO-ED study found that emergency providers perform significantly better with fundus photography than with direct ophthalmoscopy in the detection of fundus abnormalities. The authors hypothesised that by providing additional training to emergency providers, this would...
