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Risk of intraocular haemorrhage with new oral anticoagulants
The authors conducted a study to assess the risk of intraocular haemorrhage with warfarin dabigatran, rivaroxaban, apixaban. All reported cases of intraocular haemorrhage (vitreous, choroidal, or retinal) with warfarin and new oral anticoagulants (NOACs) (including dabigatran, rivaroxaban, apixaban) from the...
High dose (2.5mg) bevacizumab for postradiation cystoid macular oedema
The authors present a retrospective, interventional case series investigating the efficacy of high dose (2.5mg/0.1ml) intravitreal bevacizumab in the treatment of persistent postradiation (Iodine-125 plaque brachytherapy for uveal melanoma) cystoid macular oedema (CME). Persistent CME was defined as increased or...
RPE tears after intravitreal Lucentis
The current hypothesis regarding retinal pigment epithelium (RPE) tears is the contraction and fibrosis in choroidal neovascularisation (CNV) tissue after anti-VEGF therapy can induce rips in the overlying RPE. This South Korean study aimed to identify the association between RPE...
Long-term outcomes of intravitreal ranibizumab for neovascular AMD
This is a single centre prospective study for the long-term, whole population ‘real-world’ clinical outcomes of ranibizumab therapy in treatment-naïve patients for neovascular age-related macular degeneration (AMD). This study recorded: demographics, Early Treatment Diabetic Retinopathy Study visual acuity (ETDRS VA)...
Anterior capsular tears complicating phacoemulsification surgery
This is a retrospective, interventional case series, assessing the occurrence of anterior capsular tears in phacoemulsification surgery, its effect on outcomes and further complications. Despite being a well recognised complication of phacoemulsification surgery the authors felt that there is a...
Trabeculectomy for normal tension glaucoma
This is a retrospective consecutive, non-comparative case series of 131 eyes of 98 patients undergoing trabeculectomy between 2007 and 2013 in a normal tension glaucoma (NTG) clinic. Assessment of the clinical outcomes include intraocular pressures (IOP) reduction, bleb formation, final...
OCT angiography and retinal vein occlusions
In this retrospective, observational case series, the authors set out to evaluate the morphology of the superficial and deep capillary plexa of eyes that suffered a retinal vein occlusion (RVO) on OCT angiography (OCTA) and compare the findings with fluorescein...
Endophthalmitis after intravitreal injections in France
In this nationwide, retrospective, multicentre case series, the authors looked at the incidence and characteristics of endophthalmitis after intravitreal injections of anti-VEGFs and steroids, given for a variety of posterior segment conditions (macular oedema secondary to diabetes or retinal vein...
Hyper reflective foci (HRF) on OCT in diabetic retinopathy
This study investigated the presence of hyper reflective foci (HRF) in asymptomatic patients affected by type 1 or type 2 diabetes, separately, without clinically significant diabetic macular oedema and visual impairment. In total 71 eyes with non-proliferative diabetic retinopathy were...
Intraoperative floppy iris syndrome and prevalence of intraoperative complications
Alpha-blockers (particularly of the selective type) are known to be associated with intraoperative floppy iris (IFIS) and poor dilation, which can present in various severities during cataract surgery and need to be recognised in order to avoid intraoperative complications. Methods...
Ginko bilboa extract affects hypoxic retinal pigment epithelial cells
Wet age-related macular degeneration (AMD) is characterised by choroidal neovascular membrane (CNVM) formation. It is thought that localised hypoxia within the retina results in overexpression of growth factors such as vascular endothelial growth factor (VEGF), which induces CNVM formation. VEGF...
