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Hyper reflective foci (HRF) on OCT in diabetic retinopathy
This study investigated the presence of hyper reflective foci (HRF) in asymptomatic patients affected by type 1 or type 2 diabetes, separately, without clinically significant diabetic macular oedema and visual impairment. In total 71 eyes with non-proliferative diabetic retinopathy were...
Intraoperative floppy iris syndrome and prevalence of intraoperative complications
Alpha-blockers (particularly of the selective type) are known to be associated with intraoperative floppy iris (IFIS) and poor dilation, which can present in various severities during cataract surgery and need to be recognised in order to avoid intraoperative complications. Methods...
Coeliac disease and anterior scleritis
The authors present an interesting case report of recurrent anterior scleritis. Circulating IgA and IgG auto-antibodies directed against tissue transglutaminase, endomisium and gliadin are frequently elevated in patients with coeliac disease. The classic symptoms remain chronic diarrhoea, malabsorption syndromes and...
Intravitreal aflibercept for retinal angiomatous proliferation (RAP)
In this prospective study the authors present the visual and anatomical outcome of patients with RAP lesions who were treated with intravitreal aflibercept. The study cohort of 46 patients reached study completion at week 96. They were all Caucasians, with...
VIBIM Study: One-year results of treatment of DME with aflibercept using TnE
The VIBIM study (the treat-and-extend regimen (TER) using intravitreal aflibercept in diabetic macular edema (DME) study) was designed to evaluate the efficacy of the TER using aflibercept in the management of DME for a period of two years. The authors...
Retinal vascular occlusion from gentamicin injection post-vitrectomy
The authors present two case reports for the rare, but serious, complication of retinal vascular occlusion as a presumed result of subconjunctival injection following 25-gauge vitrectomy. Risk factors for the complication include: cardiovascular disease, retrobulbar anaesthesia, high intraocular pressure (IOP)...
Association between neurodegeneration and macular perfusion in the progression of diabetic retinopathy
In this prospective three-year longitudinal study, the authors aimed to explore the relation between retinal neurodegenerative changes and vessel closure (VC) in individuals with non-proliferative diabetic retinopathy (NPDR). The participants included 74 individuals with type 2 diabetes, NPDR, and Early...
Comparison of visual field indices between normal adults and children
The authors present a prospective observational study which aimed to compare visual field indices with retinal nerve fibre layer (RNFL) thickness using optical coherence tomography (OCT) in normal adults and children. Children aged 6–18 years were recruited from a single...SCOPE Announces 2025 Independent Prescriber Bursary Award Winners
SCOPE is proud to announce the winners of its 2025 Independent Prescriber (IP) Bursary Awards, an initiative now in its fourth year. Designed to support optometrists in gaining IP qualifications by covering course fees, the awards continue to attract strong...Everyday diabetes medicine could treat common cause of blindness
Doctors have found that metformin, an everyday medicine for diabetes, is associated with less progression of age-related macular degeneration (AMD), the commonest cause of blindness in western countries. People with diabetes over the age of 55 years taking metformin were...
