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American Journal of Ophthalmology cover image.

Intravitreal afibercept and ranibizumab for PCV

1 August 2016 | | EYE - Vitreo-Retinal
This is a retrospective, interventional series comprising 98 eyes with polypidal choroidal vasculopathy (PCV) with the aim of comparing treatments with afibercept and ranibizumab, highlighting any differences in their efficacy. Case notes and imaging (FFA / ICG / OCT) were...
Ophthalmologica journal front cover image.

Stereotactic radiotherapy for polypoidal choroidal vasculopathy

1 August 2015 | | EYE - Vitreo-Retinal
Polypoidal choroidal vasculopathy (PCV) is a variant of neovascular AMD. It is a disease of choroidal vasculature characterised by abnormal branching vascular network with aneurysmal dilatations (polyps). Features of PCV include pigment epithelial detachments (PED), subretinal fluid (SRF) accumulation and...

Demodex blepharitis: A transatlantic comparison of treatments available in the UK and US

1 April 2026 | | EYE - Cornea, EYE - Oculoplastic
Demodex blepharitis is widely recognised among eyecare professionals as an important cause of chronic lid margin inflammation, dry eye and ocular surface diseases. The characteristic feature for diagnosis is the presence of waxy deposit at the lash bases on slit...

Cataract surgery in corneal disease

3 June 2026 | | EYE - Cornea, EYE - Cataract
Cataract surgery in the presence of corneal disease presents multiple challenges, from determining whether symptoms are lenticular or corneal in origin, to decisions regarding timing of surgery, intraocular lens (IOL) power calculation, IOL selection, surgical technique and perioperative care. Realistic...

Severe conjunctival cicatrisation secondary to chronic glaucoma therapy

1 August 2015 | | EYE - Cataract, EYE - Cornea, EYE - General, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
The timing of glaucoma filteration surgery during the course of chronic progressive glaucoma remains a contentious issue amongst glaucoma specialists. The vast majority support the use of maximal medical treatment initially to achieve the target pressure. Surgical procedures are only...

The approach to angle-closure glaucoma

1 October 2016 | | EYE - Glaucoma
Further to my last article in Eye News (print issue) describing the diagnostic approaches to various clinical scenarios in glaucoma, the approach to angle-closure glaucoma (ACG), a situation terrifying for patient and registrar alike, will be discussed. Please refer to...

Cancer associated retinopathy

7 December 2020 | | EYE - Vitreo-Retinal, EYE - General
Abdul Muhyemin Tarin reviews the presentation, pathophysiology and management of this paraneoplastic syndrome. Case presentation A 60-year-old hypermetropic female patient presented with several months’ history of painless blurred vision. Visual acuity (VA) was 6/24 and 6/9-1 in right and left...

The role of inflammation in the pathophysiology of DMO

1 February 2016 | | EYE - Vitreo-Retinal
Diabetic macular oedema (DMO) is a major cause of visual loss in diabetes, with a complex multifactorial pathogenesis. In the UK alone it is estimated that there are nearly 2.5 million diabetic patients aged over 12 years. Approximately 65,000 of...

What’s next in retinal imaging? Faster, deeper and full-on

1 April 2015 | | EYE - Vitreo-Retinal, EYE - Imaging
Fast-evolving technological leaps are opening the way toward clinically useful ocular coherence angiography, generating 3-dimensional microvasculature maps without intravenous dye injection, as well as whole-eye imaging, handheld patient-operated optical coherence tomography (OCT) devices and, for challenging vitreoretinal procedures, integrated intraoperative...

A paradigm shift in the way we approach cataract surgery

1 February 2015 | | EYE - Cataract, EYE - Refractive
Cataract surgery is the most common elective surgical procedure in the UK [1], with in the region of 350,000 cases being conducted each year. With an ageing population, this figure will only continue to rise over time. Cataract surgery is...

Renewed momentum in ocular gene and cell therapy, broadening application to chronic disease

5 February 2020 | | EYE - Vitreo-Retinal, EYE - General
Gene and cell therapies offer the prospect of ground-breaking new avenues for the treatment of diseases, reflected in a renewed explosion of interest and investment in retinal gene therapy. Rod McNeil reports recent clinical trial readouts across a diverse range...

Emerging therapies for geographic atrophy: complement inhibitors show potential to slow progression and preserve RPE and photoreceptor integrity

5 June 2023 |
Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD) characterised by progressive, irreversible loss of the retinal pigment epithelium (RPE) and photoreceptors and is estimated to account for approximately 10% of AMD-related blindness [1-4]. The Age-Related Eye...