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Stromal cell alignment in damaged cornea
Stromal keratocytes are responsible for wound healing in the cornea following damage. Keratocytes at the site of injury become activated and differentiate to myofibroblasts which secrete extracellular matrix (ECM) to close the wound, a response mediated by transforming growth factor...Insights on medical AI for ophthalmology: an update on current perspectives
Artificial intelligence (AI) has immense promise for revolutionising medical practice. Generative AI is a form of AI in which algorithms are trained on datasets that can be used to generate new content, such as text, images or video based on...One bottle, many eyes: The hidden dangers of sharing eyedrops in the community
We report a case of unilateral mydriasis in a female patient referred by her general practitioner (GP) with a dilated and sluggish left pupil, likely caused by the accidental use of her husband’s prescription eyedrops. This case highlights the importance...Recurrent corneal erosions secondary to isotretinoin use
Isotretinoin (13–cis-retinoic acid) is the first line treatment for moderate to severe nodulocystic or papulopustular acne [1,2]. Although it is a safe medication, it has several adverse side-effects, including ophthalmic manifestations, as shown in Table 1 [3]. These side-effects need...
Could midbrain volume on MRI be used to guide diagnosis of progressive supranuclear palsy?
The authors present a cohort study, of patients with a likely diagnosis of progressive supranuclear palsy (PSP) using a combination of prospective assessment and retrospective review. The cohort comprised of 14 patients; the data for six patients was obtained through...
Refractive surgery for anisometropic amblyopia
The authors report the outcomes of refractive surgery with phakic intraocular lens (PIOL) implant for management of anisometropic amblyopia in children intolerant to conventional therapy. This was a retrospective study of 71 eyes of 71 patients of which 58 were...
