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Gene therapy for inherited retinal disease: the Manchester Ocular Gene Therapy Group MDT service

4 August 2021 | | EYE - Paediatrics, EYE - Vitreo-Retinal, EYE - General
The authors describe the process set up in Manchester for the optimum delivery and assessment of a new gene therapy treatment for patients with RPE65 IRD. Inherited retinal dystrophies (IRDs) are the second commonest cause of severe visual impairment in...

Streamlining cataract lists: how are you managing it?

1 October 2021 | | EYE - Cataract, EYE - Refractive, EYE - General
Mr Jonathan Ross, in conversation with Ms Bita Manzouri, provides a personal perspective on challenges and opportunities shaping the future of cataract surgery services across the hospital eye service. Redesigning cataract pathways in response to COVID-19 Bita Manzouri: Over the...

How effective is nurse-led telephone preassessment for cataract surgery?

25 July 2023 | | EYE - Cataract, EYE - Refractive
Cataract surgery is the most frequently performed surgical procedure in the UK [1]. The demand for cataract surgery is projected to increase with ageing population, and the recent pandemic has further contributed to the extended waiting times in the UK....

An interview with a glaucoma consultant: Insights for aspiring trainees

2 October 2025 | | EYE - Glaucoma
In this article, Resident Doctor Chi Kit Yan sits down with Consultant Glaucoma Specialist Salman Sadiq and explores the daily life of a glaucoma specialist, the pros and cons of the role, how trainees can prepare for this subspecialty, and...

Unilateral central scotoma following dengue fever

12 October 2023 | | EYE - Neuro-ophthalmology
Case report A 16-year-old Caucasian male was referred to the eye casualty at Nottingham University Hospitals NHS Trust by the infectious diseases unit in September 2013. He gave a history of photophobia, pain on eye movements and central blurred vision...

Diabetic Macular Oedema

1 December 2013 |
Diabetes mellitus is a metabolic disorder that affects the metabolism of all three categories of carbohydrates, lipids and proteins. This condition is characterised by chronic hyperglycaemia [1]. This can cause end organ damage. The estimated worldwide diabetes prevalence for 2010...

The power of the full blood count

1 October 2021 | | EYE - Vitreo-Retinal, EYE - General
Vishal Shah walks us through his thought process whilst highlighting the importance of routine investigations when dealing with unusual retinovascular presentations. Retinal changes can arise in anaemia, leukaemia, lymphoma, myeloproliferative and myelodysplastic syndrome. They are often the first manifestation of...

Moorfields cataract, medical retina and disc assessment

31 March 2025
The Cataract/medical retina/ disc assessment short course has been designed to meet the training needs of band 6’s and 7s who wish to develop their knowledge and skills in disease recognition, management and intervention of cataract, medical retina and disc...

Outcomes at 100 weeks from the LEAVO study of intravitreal anti-VEGF therapies for macular oedema secondary to central retinal vein occlusion

23 May 2019 |
Royal College of Ophthalmologists Annual Congress 2019, Glasgow - First presented and discussed on Monday 20 May 2019, with a further presentation of results during Retina Subspecialty Day on Thursday 23 May 2019. Among patients with macular oedema secondary to...

Aug/Sep 2015 Quiz 2

1 August 2015 | | EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
History A two-year-old female child presented with loss of vision in her left eye. Examination showed leukocoria and intraocular calcification was identified on scanning. The suspected diagnosis was intraocular retinoblastoma and the child underwent an enucleation. The eyeball was submitted...

Melanocytoma of the optic disc

1 June 2015 | | EYE - Cataract, EYE - Cornea, EYE - General, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
Melanocytoma is a heavily pigmented lesion, composed of melanocytes and is a variant of melanocytic naevus. It classically occurs at the optic disc and is usually benign, static and asymptomatic. However, it can occasionally grow and invade the retina or...

Traumatic ‘toy’ gun injury leading to permanent vision loss

6 April 2021 |
Pseudoxanthoma elasticum (PXE) is a progressive, inherited disorder of connective tissue that affects the skin, cardiovascular system and retina. Ocular manifestations of the disease are related to Bruch’s membrane, a thin elastic tissue layer located between the retinal pigment epithelium...