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4714 results found

Microperimetry of subretinal drusenoid deposits

Subretinal drusenoid deposits (SDD), originally termed ‘reticular pseudo-drusen’, have recently been identified by histology and optical coherence tomography (OCT) as aggregations located in the subretinal rather than the sub retinal pigment epithelium (RPE) space. These deposits affect the amount of...

Scheimpflug vs. OCT in measuring corneal thickness

The authors report on the reproducibility and repeatability of corneal thickness measurements using three different Scheimpflug imaging cameras (Pentacam, Sirius and Galilei) and one Fourier-domain optical coherence tomography (OCT) system (RTvue-100). The rationale for this study is that corneal thickness...

Translucent vs. lightproof occluders

This study investigates the change in visual acuity following occlusion in amblyopes and non-amblyopes using translucent versus lightproof occlusion of the dominant eye. Group 1 non-amblyopes consisted of 26 subjects: 16 visually normal and 10 strabismic or anisometropic subjects without...

Saccadic differences under cover test

Patients with intermittent exotropia and exophoria plus ortho subjects underwent measurement of saccadic reaction times (SRTs) to compare those occurring in one eye and those occurring with alternating cover tests (ACTs). Twenty-five subjects were studied. Results for the intermittent exotropia...

Impact of orthoptic re-exam in screening

The authors evaluated whether the re-examination within the orthotic screening in children with questionable results at the first examination can reduce the number of submissions to specialists and avoid a high number of false positives. This was a retrospective study...

Photoscreening comparison

The A09/S09 photoscreener contains a fixation target of flashing lights (as for the S04) plus a smiley face which is new. Concerns were raised that the smiley face may stimulate less accommodation than the S04 attention lights and therefore potentially...

Quality of esotropia referrals

The purpose was to examine the quality of referrals made for children with esotropia and to evaluate management offered prior to referral. This retrospective study identified 326 children with esotropia aged less than five years and referred over a period...

Density of cataract and its influence on retinal nerve fibre layer thickness

The aim of this study was to further define and model the influence of cataract on spectral domain optical coherence tomography (SDOCT) image quality and retinal nerve fibre layer (RNFL) thickness measurements. OCT quality is influenced by opacities in the...

Short-term outcome after intravitreal ranibizumab injections for ROP

This is an interventional case series study of three premature babies (six eyes) with high risk prethreshold or threshold retinopathy of prematurity (ROP) with plus disease that received intravitreal ranibizumab injections for ROP. All infants received intravitreal ranibizumab injections of...

HtrA1 enhances cell senescence

A genetic basis for age-related macular degeneration (AMD) has been greatly advanced in recent years. The role of identified pathways such as complement factor H in AMD has been widely investigated. However, the effect of other gene variants identified by...

Nanoparticle administration of latanoprost

Glaucoma is a progressive optic neuropathy characterised by increased ocular pressure and loss of retinal ganglion cells. Conventional drug therapy with eye drops to reduce intraocular pressure (IOP) has variable bioavailability and can lead to ocular surface disease. In this...

Oral proton pump inhibitors in macular degeneration patients

The authors report five patients with advanced wet macular degeneration and poor vision with onset or enhancement of visual hallucinations with the use of proton pump inhibitors for heartburn management. The hallucinations were reversible with discontinuation of medication. The authors...