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A novel computerised portable pupillometer detects and quantifies relative afferent pupillary defect

We have all had referrals from A&E telling us that a patient can’t see out of one eye. Sleepily we may ask “Is there an relative afferent pupillary defect (RAPD)?” to evaluate the seriousness of the presentation. The response is...

Submacular haemorrhage associated with nAMD: A meta-analysis and meta-regression on use of tPA and anti-VEGFs

The aim of this study was to evaluate the efficacy of a combination of tPA and anti-VEGF in the treatment of submacular haemorrhage (SMH) associated with neovascular age-related macular degeneration (nAMD). A systematic review meta-analysis following PRISMA guidelines, focusing on...

Preoperative povidone iodine: weighing the risks

Following on from our recent online survey, the authors examine the potential risks and benefits of diluting the concentration preoperative povidone iodine. Povidone iodine (PI) is an iodophore that has an established use as a broad-spectrum antiseptic, mainly for the...

Intravitreal afibercept and ranibizumab for PCV

This is a retrospective, interventional series comprising 98 eyes with polypidal choroidal vasculopathy (PCV) with the aim of comparing treatments with afibercept and ranibizumab, highlighting any differences in their efficacy. Case notes and imaging (FFA / ICG / OCT) were...

Aug/Sep 2015 Quiz 2

History A two-year-old female child presented with loss of vision in her left eye. Examination showed leukocoria and intraocular calcification was identified on scanning. The suspected diagnosis was intraocular retinoblastoma and the child underwent an enucleation. The eyeball was submitted...

Development of retinoblastoma care in Indonesia and the role of multidisciplinary team meetings

In the second article of a two-part series (See Part 1 here), the authors focus on the diagnosis and management of retinoblastoma in Indonesia. COVID-19 doesn’t get thanked for many things, but on 19 December 2020 as the world grew...

My Top Five: Promising gene therapies for ocular conditions

Gene therapy, a pivotal advancement in modern medicine, particularly shines in ophthalmology. By targeting defective genes with engineered vectors, this approach promises significant strides in treating inherited retinal diseases. This article reviews the top five gene therapies in late-stage trials,...

My Top Five: Promising gene therapies for ocular conditions

Gene therapy, a pivotal advancement in modern medicine, particularly shines in ophthalmology. By targeting defective genes with engineered vectors, this approach promises significant strides in treating inherited retinal diseases. This article reviews the top five gene therapies in late-stage trials,...

The power of the full blood count

Vishal Shah walks us through his thought process whilst highlighting the importance of routine investigations when dealing with unusual retinovascular presentations. Retinal changes can arise in anaemia, leukaemia, lymphoma, myeloproliferative and myelodysplastic syndrome. They are often the first manifestation of...

RNIB volunteers “honoured” to meet HM The King and HM The Queen

Two volunteers with sight loss visited Windsor earlier this month to meet Royalty and explain how volunteering can bring communities together. Jonathan Abro and Simon Holt, who both volunteer for RNIB (Royal National Institute of Blind People), were part of...

The extended role of the specialist ophthalmic photographer

The prevalence of certain retinal conditions such as diabetic retinopathy and age-related macular degeneration (ARMD) is projected to grow substantially over the next decades. Estimates for the projected growth in burden on eye services for diabetic retinopathy and neovascular ARMD...

Preparing for the Duke Elder Award

The Duke Elder examination is an undergraduate ophthalmology exam, conducted by the Royal College of Ophthalmologists (RCOphth) and undertaken by students with an interest in ophthalmology. It is a two-hour, 90-question, multiple choice exam with a broader curriculum than that...