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The effect of everolimus on retinal pigment epithelium and proliferative vitreo-retinopathy
The principal cells involved in proliferative vitreo-retinopathy (PVR) are retinal pigment epithelial cells (RPE). Everolimus is a drug used in renal cell carcinoma which targets and inhibits a key regulatory protein in cancer (mTOR). In this study, the authors investigated...
Understanding the pachychoroid disease spectrum
This article provides a comprehensive review of the pachychoroid disease spectrum, a group of chorioretinal disorders characterised by abnormal choroidal thickening and various pathological changes in the choroid, retinal pigment epithelium, and retina. It also highlights the controversies and knowledge...GDPR, email and private practice
A new set of data protection regulations became law in the EU (including the UK) in May 2018. General Data Protection Regulation (GDPR) replaces the 1988 Data Protection Act. The regulation brings new rights and expectations about how our personal...Preparing to start as a consultant
I was just coming to the end of a fantastic glaucoma fellowship at Moorfields, during which Samad Ansari had been a colleague and friend, and soon to start as a consultant in Oxford where Rebecca Turner is Clinical Director, and...
Systemic and Ophthalmic Management of Diabetes Mellitus
Chris Steele, the Head of Optometry in Sunderland Eye Infirmary, has a wealth of experience and knowledge in retinal pathology and has recently published what is now his second book on diabetes. This has been a major undertaking, taking three...Embryology in clinical practice
The fascinating world of embryology is both beautiful and practical. It is a home video of our evolutionary history through the ages from the single cell through to the life aquatic, the development of gut, limbs and brain, and most...New UK study finds widespread hidden sensory loss
One in four over-50s has vision impairment and three quarters have some hearing loss. Groundbreaking research involving eye tests and hearing examinations with more than 500 over-50’s – the first of its kind in the UK – has revealed widespread...Irido-corneal endothelial syndrome: an overview
Irido-corneal endothelial (ICE) syndrome is a rare group of eye related disorders that constitute three different clinical entities: Chandler syndrome (CS), essential / progressive iris atrophy and iris naevus / Cogan-Reese syndrome. ICE syndrome is sporadic in its presentation as...Survey reveals poor public awareness of dry eye disease
A new survey has revealed how few people are aware of Dry Eye Disease, a debilitating and painful eye condition which affects one in four people in the UK.Large-scale study uncovers demographic and sex factors behind genetic cause of age-related visual loss
A new study has identified a major genetic contributor to Fuchs’ Endothelial Corneal Dystrophy (FECD), a common cause of vision loss, also highlighting the significant roles of sex and ancestry. FECD is a common, inherited eye condition that primarily affects...
Comparison of bilateral lateral and unilateral recession resection for IXT
This is a retrospective review study of patients between the ages of three and 15 years old with the basic type of intermittent exotropia (IXT) who had strabismus surgery between January 2003 to September 2009. There were 85 patients included...
