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3064 results found

5-FU in cicatricial conjunctivitis

This is a retrospective review of 56 patients with cicatricial conjunctivitis, including 25 eyes that received sub-conjunctival injections of 25-50mg of 5-fluorouracil (5-FU) as part of their treatment. Thirty-seven patients had ocular cicatricial pemphigoid (OCP) and 19 had Stevens-Johnson syndrome...

BT for retinal detachment strabismus (2020)

The authors report updated experience on factors influencing botulinum toxin (BT) outcomes for strabismus following retinal detachment surgery. This was a retrospective review of 32 patients with follow-up of 20 months (1-132). Mean age at BT injection was 44 years...

Long-term use of botulinum toxin for hemifacial spasm and blepharospasm

The authors conducted a retrospective review of clinical / procedure documentation for consecutive blepharospasm (BEB) and hemifacial spasm (HFS) patients undergoing treatment with onabotulinum toxin A (Botox) in one clinic setting over the past 20 years. They report on the...

Efficacy of augmented-dosed surgery versus botulinum toxin A injection for acute acquired concomitant esotropia

This is a retrospective study of 104 patients diagnosed with acute acquired concomitant esotropia (AACE) between 2020 and 2022. Potential factors that influence the dose-response of bilateral medial rectus recession (MRec) and the rate and risk factors for ACCE relapse...

Long-term treatment for diabetic macular oedema

The authors set out to characterise anti-VEGF treatment patterns and long-term outcomes in patients with diabetic macular oedema. A retrospective analysis of over 190 thousand patients on the Intelligent Research in Sight registry was performed. Of these, 1236 eyes have...

Results of bilateral medial rectus recession combined with either BT or bridge Faden when treating large angle strabismus

In a series of 26 patients (11 female, 15 male) with large angle esotropia >35PD, the authors compared results of botulinum toxin A (BTA) and bridge Faden operation combined with bilateral medial rectus (BMR) recession. Overall age of surgery was...

Anti-VEGF injections and macular atrophy progression in patients with nAMD in remission

This is a retrospective study of 59 eyes with neovascuar age-related macular degeneration (nAMD) with at least 6-month remission, to determine the effect of continuing anti-VEGF injections on the progression of macular atrophy (MA) during remission of nAMD. Group 1...

BTA as a first-line treatment option for acute acquired comitant esotropia

This study presents results of a single-centre institute use of botulinum toxin A (BTA) as an initial treatment choice for acute acquired comitant esotropia (AACE). This was a prospective observational case series study of 72 patients (49 male, 23 female)...

Artificial intelligence and oculomics: Improving global health

The application of artificial intelligence (AI), and in particular deep learning, to high-resolution ocular imaging has led to many new discoveries, enabling the prediction of multiple different systemic diseases from ocular biomarkers. This emerging field is known as ‘oculomics’ [1]....

Cataract surgery training in the independent sector

I am now most of the way through my ST3 year working in Plymouth, within the Peninsula Deanery. Before the start of the year, I was approached by one of my consultants who asked if I would like to carry...

Lothian Optometry Teach and Treat Clinic

The Lothian Optometry Teach and Treat (LOTT) Clinic is a supervised training clinic for community optometrists with an interest in managing patients with acute eye pathology, normally managed in the hospital setting. LOTT, which is the first clinic of its...

The last three patients: dermatology (Patient Three)

For the third and final reflection in this series (see Part 1 and Part 2), Professor Jonathan Rees recounts his experience of a patient with cancer who was failed by the NHS, and how their inadequate treatment illuminates some issues...