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OCT in proliferative diabetic retinopathy

This report set out to describe the anatomical relationships between retinal neovascular complexes (NVC), the posterior vitreous, and the vitreoretinal interface in patients with proliferative diabetic retinopathy using spectral domain OCT. The following was recorded for each NVC 1) posterior...

Chronic lymphocytic leukaemia (CLL) of the lacrimal sac

The authors present a case series of three patients with known CLL, two of which presented with mass and epiphora and one case with epiphora alone. All three patients had initially being diagnosed and were treated for chronic dacryocystitis. Histopathological...

Transcriptomic analysis of ocular tissues

Transcriptomics is defined as the analysis of the complete set of RNA transcripts present in a cell under different circumstances, quiescent versus challenge, by microarray analysis. Comparison of transcriptomes identifies genes that are differentially expressed in different cell populations under...

Retinal ischaemia on OCTA and diabetic retinopathy grade

The authors quite rightly point out that quantification of retinal ischaemia has the potential to serve as a biomarker for diabetic retinopathy disease progression. They set out to investigate the relationship between area of ischaemia on a swept source OCTA...

Effects of ML4 on the eye

Mucolipidosis type IV (ML4) is an autosomal recessive lysosomal storage disease and is caused by variants of the MC0LN1 gene. It often presents in young individuals with eye and ocular adnexa issues. The authors present a case report and literature...

Can a dose scale be calculated for the modified Harado-Ito procedure?

The aim of this study was to review the surgical outcomes of the Fells modified Harado-Ito procedure using a dose scale approach with long-term follow-up, and to evaluate the relationship between preoperative factors and final outcome. This was a retrospective...

Experiences of patients and their families and the impact of Leber hereditary optic neuropathy

The authors present a qualitative study which aimed to explore the impact of Leber hereditary optic neuropathy (LHON) from diagnosis to present day on both patients and their families. Individuals with LHON and their families were purposively sampled from four...

Age-related distance esotropia – what are the clinical characteristics?

The authors present a retrospective case review of individuals with primary divergence insufficiency or age-related distance esotropia, over a 15-year period. Inclusion criteria allow for the difference between near and distance angles to be patient reported or objectively measured. One...

Beyond ‘Shield and Ship’: a novel device (Eye-Aid) to provide temporary aqueous tamponade

The authors present a pilot efficacy study of the novel Eye-Aid device in a porcine model of full-thickness corneal wounds to mitigate anterior chamber collapse in the forward military environment. Currently, the ‘Shield and Ship’ paradigm taught to military healthcare...