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Comparison of in-person and telephone appointments for week 1 postoperative follow-up
This study evaluated engagement with a postoperative week-1 follow-up phone call, assessing safety, cost and travel savings. Electronic medical records of children (<18 years) having undergone strabismus surgery with a single surgeon during a 4-year period, were reviewed. Patients were...
IO surgery
The purpose of this paper was to evaluate the efficacy of a new surgical technique in reducing inferior oblique muscle overaction (IOOA) consisting of suturing the muscle to the sclera at the Gobin point with tendon sparing and using a...
Methotrexate and mycophenolate mofetil for non-infectious uveitis
This is the first reported randomised clinical trial comparing methotrexate versus mycophenolate mofetil (MMF) for the treatment of non-infectious intermediate uveitis, posterior uveitis or panuveitis. To be eligible for recruitment, patients had to be on ≥15mg oral prednisone and demonstrated...
Investigating MOG-IgG as a cause for optic perineuritis
Optic perineuritis can be a manifestation of infectious and systemic inflammatory disorders, but in most cases is considered idiopathic. Diagnosis is established by magnetic resonance imaging (MRI) with the demonstration of optic nerve sheath enhancement with sparing of the optic...
Treatment efficacy of stage 4 ROP
This study aimed to determine the efficacy of combined vitrectomy and anti-VEGF injection for advanced stage 4 ROP with extensive neovascular proliferation (NF). The study included nine infants; six bilateral and three unilateral. Seven were female and the mean gestational...
Management of ocular surface disease
This is a retrospective study of patients with ocular surface disease (OSIDs) treated with IKERVIS in a single centre between 2016 to 2019 with at least six months follow-up. Clinical outcome was defined as successful (resolved or stable disease), active...
Real-world experience of using ciclosporin-A 0.1% in the management of ocular surface inflammatory diseases
This is a retrospective study of patients with ocular surface inflammatory diseases (OSIDs) treated with IKERVIS in a single centre between 2016 to 2019 with at least six months follow-up. Clinical outcome was defined as successful (resolved or stable disease),...
Aquaporin-4 antibody testing in isolate optic neuritis
The authors present a retrospective case review of first presentation isolated cases of optic neuritis tested for aquaporin-4 antibody across two centres over a nine-year period. Exclusion criteria included known diagnosis or other manifestations of neuromyelitis optica spectrum disorder. Two...
Tocilizumab in Graves’ orbitopathy
This prospective European study looks at the response to tocilizumab in corticosteroid-resistant disease. Tocilizumab (TCZ) is a monoclonal antibody that competitively inhibits IL-6 binding to its receptor. Unlike teprotumumab, the advantage of TCZ is that it is already used within...
Comparison of bupivacaine injection vs. mini-tenotomy for small angle deviations
Bupivacaine hydrochloride is an aminoacyltype local anaesthetic. Injection into extraocular muscles elicits a myotoxic response destroying striated muscle fibres but sparing satellite cells, nerves and vessels. Preserved satellite cells proliferate to form new muscle fibres, causing muscle hypertrophy and greater...
Tocilizumab effectiveness in paediatric non-infectious uveitis: data from the International AIDA Network Registries on ocular inflammatory disorders
Medical records of 15 paediatric patients (onset before age of 16) affected by refractory non-infectious uveitis (NIU) and treated by tocilizumab (TCZ) were reviewed. Data were extracted from the international AIDA Network for uveitis registry and Behcet’s disease registries. They...
