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Intravitreal ranibizumab for the treatment of myopic CNV

The authors conducted a prospective study. Sixty-four patients (65 eyes) attended the 12-month follow-up examination. The mean patient age was 47.8 years. Fifty-five patients (86.0%) were females. All patients had pathologic myopia (a spherical equivalent of more than − 6.0...

How to get the most out of your medical school ophthalmology placement

Ophthalmology has become a very popular speciality, generating a vast interest amongst medical students with competition for training posts increasing yearly. Yet it is often difficult to get adequate exposure to the speciality prior to applications, with very limited time...

The importance of ‘hands-on’ learning

Providing ongoing professional education and development for the allied professions out of the clinic or hospital setting is often quite challenging. The reorganisation of rotas, heavy clinic lists and financial constraints all add up to making the opportunity to learn...

Ophtherminator 3 - Rise of the Machines

“Bring back life form, priority one, all other priorities are rescinded.” Film buffs will spot this as a chilling quote spoken by Ash (Ian Holm) from the classic sci-fi horror movie Alien (1979). Ash (spoiler alert) is a Hyperdyne Systems...

CRATER 2025

The Conference on Recent Advances in Translational Eye Research 2025

Corneal lenticule allotransplant

This animal study looked at corneal lenticule allograft transplantation in rabbits. Seven rabbits underwent small incision lenticule extraction (SMILE) procedures, where their stromal lenticules were extracted and transplanted fresh into pre-prepared corneal stromal pockets of seven recipient eyes. Animals were...

Retinal ganglion cell loss in diabetes and diabetic retinopathy

The aim of this observational case control study was to evaluate the association of diabetes and diabetic retinopathy (DR) with retinal ganglion cell loss. Cases were Chinese patients with type 2 diabetes with and without DR, aged 40-80 years. Eligible...

Using OCT to screen and monitor Alzheimer’s disease

Alzheimer’s disease (AD) is a neurodegenerative illness characterised by progressive decline in cognitive function. AD is the main cause of dementia worldwide. Over recent years researchers have strived to find biomarkers to diagnose AD, particularly in the early stages of...

High myopia macular thickness

The purpose of this study was to compare macular thickness and volume in 15 highly myopic (>-6D) young children with 11 age-matched controls (-2 to +4D refractive errors) using Stratus third generation OCT. Mean spherical equivalent was -9.42 ±2.81D for...

Amblyopic choroidal thickness

The authors studied choroidal thickness in 38 paediatric cases (76 eyes) with unilateral amblyopia to evaluate the differences between amblyopic and fellow eyes, and compare them with 19 healthy control subjects (38 eyes). Anisometropic amblyopia was present in 17 cases...

Choroidal defects in neurofibromatosis

The aim of this study was to investigate the frequency of choroidal abnormalities using infrared reflectance imaging with optical coherence tomography (OCT) in paediatric patients with neurofibromatosis (NF) type 1. Thirty-eight eyes of 19 patients were reviewed. NF1 was diagnosed...

Gender and ethnicity related differences in optic nerve head

The authors investigated the effect of ethnicity and gender on optic nerve head morphology comparing Indian and Caucasian males and females. The optic nerve head was investigated using spectral-domain optic coherence tomography (SD-OCT). Results showed that disc and rim areas...