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A review of chromosome 9p21 POAG susceptibility locus
Primary open angle glaucoma (POAG) is a genetically complex disease and the overall phenotype is influenced by multiple traits including intraocular pressure (IOP), central corneal thickness and structural features of the optic nerve head. Therefore, genes affecting any of these...Exploiting nature’s randomised trials of eye disease
Confounding and reverse causation in observational ophthalmic epidemiology Traditional observational studies are inherently limited in establishing a causal effect of an exposure on an outcome of interest. One fundamental limitation is confounding, whereby causation is incorrectly attributed to a third...Practice Plus Group: Identifying candidates for combined glaucoma and cataract surgery: an advanced approach
Practice Plus Group is delighted to offer an accredited event for local referrers: ‘Identifying candidates for combined glaucoma and cataract surgery: an advanced approach’ During this course, we will delve into the complex interplay between Glaucoma and Cataract, exploring how...
Eye drop prescription and usage in glaucoma patients
The authors describe a study using a questionnaire to determine how patients use their glaucoma medications to investigate the association between patterns of eye drop prescriptions and medication use. They enrolled 67 Japanese patients who had been prescribed topical anti-glaucoma...
Risk factors and untreated POAG
The authors examined 50 untreated open angle glaucoma patients to determine if there was an association between the level of glaucomatous damage and documented risk factors. In this study the authors measured the extent of morphologic and functional glaucomatous damage...
Association between diabetes mellitus and dry eye disease
Diabetes mellitus (DM) is currently one of the most prevalent chronic diseases in the United States. It is estimated that 12.3% of Americans suffer from DM. In this study the authors compare between dry eye and diabetes mellitus among a...
Relationship between intraocular pressure and optic nerve damage in optic nerve drusen
The authors present a retrospective study exploring the relationship between intraocular pressure (IOP) and optic nerve damage in patients with optic nerve drusen. The aim was to evaluate if patients with normal ocular pressure at the time of optic nerve...
Smartphone use in adolescents and association with ocular symptoms and binocular issues
In this study, the proportion of ocular symptoms and binocular dysfunction was evaluated to determine their association with smartphone use on adolescents aged 10–19 years. This was a cross-sectional study of 123 participants (52% male, 48% female) with a mean...Evolving towards an interventional glaucoma mindset
Traditionally, a newly diagnosed glaucoma patient would be treated first with medical therapy. As the disease progressed or the initial intervention failed to adequately control intraocular pressure (IOP), clinicians would add more drops, selective laser trabeculoplasty (SLT), repeated SLT and...
Myopia rate of change from 5-20 years
Data was collected from the 2008-12 KNHANES survey and the study included 7695 of 9351 subjects with refractive data. The mean age was 11.8 years (5-20 range) with 48.2% female. Mean spherical equivalent was -1.82 ±2.23D. For five-year-olds, the mean...
Idiopathic orbital pseudotumor as first sign of systemic inflammatory disease
The authors describe four children in whom idiopathic orbital pseudotumor (IOP) was the initial solitary finding with systemic inflammatory disease developing later. Four children were seen over a five-year period. Mean age was 9.75 years (2-14). Three were white and...
